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Intrinsically disordered domain of transcription factor TCF-1 is required for T cell developmental fidelity.
Goldman N, Chandra A, Johnson I, Sullivan MA, Patil AR, Vanderbeck A, Jay A, Zhou Y, Ferrari EK, Mayne L, Aguilan J, Xue HH, Faryabi RB, John Wherry E, Sidoli S, Maillard I, Vahedi G. Goldman N, et al. Among authors: faryabi rb. Nat Immunol. 2023 Oct;24(10):1698-1710. doi: 10.1038/s41590-023-01599-7. Epub 2023 Aug 17. Nat Immunol. 2023. PMID: 37592014 Free PMC article.
The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR + CD8 + effector state and its deletion improves checkpoint blockade.
McClory SE, Bardhan O, Rome KS, Giles JR, Baxter AE, Xu L, Gimotty PA, Faryabi RB, Wherry EJ, Pear WS, Jordan MS. McClory SE, et al. Among authors: faryabi rb. bioRxiv [Preprint]. 2023 Feb 16:2023.02.16.528833. doi: 10.1101/2023.02.16.528833. bioRxiv. 2023. Update in: Cell Rep. 2023 Aug 29;42(8):112905. doi: 10.1016/j.celrep.2023.112905 PMID: 36824931 Free PMC article. Updated. Preprint.
35 results