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Loss of 3-O-sulfotransferase enzymes, Hs3st3a1 and Hs3st3b1, reduces kidney and glomerular size and disrupts glomerular architecture.
Patel VN, Ball JR, Choi SH, Lane ED, Wang Z, Aure MH, Villapudua CU, Zheng C; NIDCD/NIDCR Genomics and Computational Biology Core; Bleck C, Mohammed H, Syed Z, Liu J, Hoffman MP. Patel VN, et al. Among authors: villapudua cu. Matrix Biol. 2024 Nov;133:134-149. doi: 10.1016/j.matbio.2024.06.006. Epub 2024 Jun 27. Matrix Biol. 2024. PMID: 38944161 Free article.
Immunomodulation of salivary gland function due to cancer therapy.
Costa-da-Silva AC, Villapudua CU, Hoffman MP, Aure MH. Costa-da-Silva AC, et al. Among authors: villapudua cu. Oral Dis. 2024 May 2:10.1111/odi.14972. doi: 10.1111/odi.14972. Online ahead of print. Oral Dis. 2024. PMID: 38696474 Review.
FGFR2b is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation.
Aure MH, Symonds JM, Villapudua CU, Dodge JT, Werner S, Knosp WM, Hoffman MP. Aure MH, et al. Among authors: villapudua cu. Res Sq [Preprint]. 2023 Feb 16:rs.3.rs-2557484. doi: 10.21203/rs.3.rs-2557484/v1. Res Sq. 2023. Update in: Nat Commun. 2023 Oct 14;14(1):6485. doi: 10.1038/s41467-023-42243-0 PMID: 36824936 Free PMC article. Updated. Preprint.