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Page 1
Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer.
Virassamy B, Caramia F, Savas P, Sant S, Wang J, Christo SN, Byrne A, Clarke K, Brown E, Teo ZL, von Scheidt B, Freestone D, Gandolfo LC, Weber K, Teply-Szymanski J, Li R, Luen SJ, Denkert C, Loibl S, Lucas O, Swanton C, Speed TP, Darcy PK, Neeson PJ, Mackay LK, Loi S. Virassamy B, et al. Among authors: speed tp. Cancer Cell. 2023 Mar 13;41(3):585-601.e8. doi: 10.1016/j.ccell.2023.01.004. Epub 2023 Feb 23. Cancer Cell. 2023. PMID: 36827978 Free article.
Genomic characterisation of hormone receptor-positive breast cancer arising in very young women.
Luen SJ, Viale G, Nik-Zainal S, Savas P, Kammler R, Dell'Orto P, Biasi O, Degasperi A, Brown LC, Láng I, MacGrogan G, Tondini C, Bellet M, Villa F, Bernardo A, Ciruelos E, Karlsson P, Neven P, Climent M, Müller B, Jochum W, Bonnefoi H, Martino S, Davidson NE, Geyer C, Chia SK, Ingle JN, Coleman R, Solbach C, Thürlimann B, Colleoni M, Coates AS, Goldhirsch A, Fleming GF, Francis PA, Speed TP, Regan MM, Loi S. Luen SJ, et al. Among authors: speed tp. Ann Oncol. 2023 Apr;34(4):397-409. doi: 10.1016/j.annonc.2023.01.009. Epub 2023 Jan 25. Ann Oncol. 2023. PMID: 36709040 Free PMC article.
Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer.
Weeden CE, Gayevskiy V, Marceaux C, Batey D, Tan T, Yokote K, Ribera NT, Clatch A, Christo S, Teh CE, Mitchell AJ, Trussart M, Rankin L, Obers A, McDonald JA, Sutherland KD, Sharma VJ, Starkey G, D'Costa R, Antippa P, Leong T, Steinfort D, Irving L, Swanton C, Gordon CL, Mackay LK, Speed TP, Gray DHD, Asselin-Labat ML. Weeden CE, et al. Among authors: speed tp. Cancer Cell. 2023 May 8;41(5):837-852.e6. doi: 10.1016/j.ccell.2023.03.019. Epub 2023 Apr 21. Cancer Cell. 2023. PMID: 37086716 Free article.
Retinoic acid and TGF-β orchestrate organ-specific programs of tissue residency.
Obers A, Poch T, Rodrigues G, Christo SN, Gandolfo LC, Fonseca R, Zaid A, Kuai JEY, Lai H, Zareie P, Yakou MH, Dryburgh L, Burn TN, Dosser J, Buquicchio FA, Lareau CA, Walsh C, Judd L, Theodorou MR, Gutbrod K, Dörmann P, Kingham J, Stinear T, Kallies A, Schroeder J, Mueller SN, Park SL, Speed TP, Satpathy AT, Phan TG, Wilhelm C, Zaph C, Evrard M, Mackay LK. Obers A, et al. Among authors: speed tp. Immunity. 2024 Nov 12;57(11):2615-2633.e10. doi: 10.1016/j.immuni.2024.09.015. Epub 2024 Oct 14. Immunity. 2024. PMID: 39406245
Stem cell plasticity, acetylation of H3K14, and de novo gene activation rely on KAT7.
Kueh AJ, Bergamasco MI, Quaglieri A, Phipson B, Li-Wai-Suen CSN, Lönnstedt IM, Hu Y, Feng ZP, Woodruff C, May RE, Wilcox S, Garnham AL, Snyder MP, Smyth GK, Speed TP, Thomas T, Voss AK. Kueh AJ, et al. Among authors: speed tp. Cell Rep. 2023 Jan 31;42(1):111980. doi: 10.1016/j.celrep.2022.111980. Epub 2023 Jan 14. Cell Rep. 2023. PMID: 36641753 Free article.
Venetoclax Dose Escalation Rapidly Activates a BAFF/BCL-2 Survival Axis in Chronic Lymphocytic Leukemia.
Luo MX, Tan T, Trussart M, Poch A, Nguyen MT, Speed TP, Hicks DG, Bandala-Sanchez E, Peng H, Chappaz S, Slade C, Utzschneider DT, Koldej RM, Ritchie D, Strasser A, Thijssen R, Ritchie ME, Tam CSL, Lindeman GJ, Huang DCS Professor, Lew TE, Anderson MA, Roberts AW, Teh CE, Gray DHD. Luo MX, et al. Among authors: speed tp. Blood. 2024 Oct 29:blood.2024024341. doi: 10.1182/blood.2024024341. Online ahead of print. Blood. 2024. PMID: 39471335
Divergent molecular networks program functionally distinct CD8+ skin-resident memory T cells.
Park SL, Christo SN, Wells AC, Gandolfo LC, Zaid A, Alexandre YO, Burn TN, Schröder J, Collins N, Han SJ, Guillaume SM, Evrard M, Castellucci C, Davies B, Osman M, Obers A, McDonald KM, Wang H, Mueller SN, Kannourakis G, Berzins SP, Mielke LA, Carbone FR, Kallies A, Speed TP, Belkaid Y, Mackay LK. Park SL, et al. Among authors: speed tp. Science. 2023 Dec;382(6674):1073-1079. doi: 10.1126/science.adi8885. Epub 2023 Nov 30. Science. 2023. PMID: 38033053
256 results