Fernandes PA - Search Results

1

Structure-Activity Relationship Studies of 9-Alkylamino-1,2,3,4-tetrahydroacridines against Leishmania (Leishmania) infantum Promastigotes.

Silva CFM, Leão T, Dias F, Tomás AM, Pinto DCGA, Oliveira EFT, Oliveira A, Fernandes PA, Silva AMS. Silva CFM, et al. Among authors: fernandes pa. Pharmaceutics. 2023 Feb 16;15(2):669. doi: 10.3390/pharmaceutics15020669. Pharmaceutics. 2023. PMID: 36839991 Free PMC article.

2

Mechanism of formation of the internal aldimine in pyridoxal 5'-phosphate-dependent enzymes.

Oliveira EF, Cerqueira NM, Fernandes PA, Ramos MJ. Oliveira EF, et al. Among authors: fernandes pa. J Am Chem Soc. 2011 Oct 5;133(39):15496-505. doi: 10.1021/ja204229m. Epub 2011 Sep 13. J Am Chem Soc. 2011. PMID: 21854048

3

Detection of farnesyltransferase interface hot spots through computational alanine scanning mutagenesis.

Perez MA, Sousa SF, Oliveira EF, Fernandes PA, Ramos MJ. Perez MA, et al. Among authors: fernandes pa. J Phys Chem B. 2011 Dec 29;115(51):15339-54. doi: 10.1021/jp205481y. Epub 2011 Dec 2. J Phys Chem B. 2011. PMID: 22060104

4

Receptor-based virtual screening protocol for drug discovery.

Cerqueira NM, Gesto D, Oliveira EF, Santos-Martins D, Brás NF, Sousa SF, Fernandes PA, Ramos MJ. Cerqueira NM, et al. Among authors: fernandes pa. Arch Biochem Biophys. 2015 Sep 15;582:56-67. doi: 10.1016/j.abb.2015.05.011. Epub 2015 Jun 1. Arch Biochem Biophys. 2015. PMID: 26045247 Review.

5

Cholesterol Biosynthesis: A Mechanistic Overview.

Cerqueira NM, Oliveira EF, Gesto DS, Santos-Martins D, Moreira C, Moorthy HN, Ramos MJ, Fernandes PA. Cerqueira NM, et al. Among authors: fernandes pa. Biochemistry. 2016 Oct 4;55(39):5483-5506. doi: 10.1021/acs.biochem.6b00342. Epub 2016 Sep 23. Biochemistry. 2016. PMID: 27604037 Review.

6

α-Glucosidase inhibition by flavonoids: an in vitro and in silico structure-activity relationship study.

Proença C, Freitas M, Ribeiro D, Oliveira EFT, Sousa JLC, Tomé SM, Ramos MJ, Silva AMS, Fernandes PA, Fernandes E. Proença C, et al. Among authors: fernandes pa, fernandes e. J Enzyme Inhib Med Chem. 2017 Dec;32(1):1216-1228. doi: 10.1080/14756366.2017.1368503. J Enzyme Inhib Med Chem. 2017. PMID: 28933564 Free PMC article.

7

Inhibition of protein tyrosine phosphatase 1B by flavonoids: A structure - activity relationship study.

Proença C, Freitas M, Ribeiro D, Sousa JLC, Carvalho F, Silva AMS, Fernandes PA, Fernandes E. Proença C, et al. Among authors: fernandes pa, fernandes e. Food Chem Toxicol. 2018 Jan;111:474-481. doi: 10.1016/j.fct.2017.11.039. Epub 2017 Nov 22. Food Chem Toxicol. 2018. PMID: 29175190

8

Evaluation of a flavonoids library for inhibition of pancreatic α-amylase towards a structure-activity relationship.

Proença C, Freitas M, Ribeiro D, Tomé SM, Oliveira EFT, Viegas MF, Araújo AN, Ramos MJ, Silva AMS, Fernandes PA, Fernandes E. Proença C, et al. Among authors: fernandes pa, fernandes e. J Enzyme Inhib Med Chem. 2019 Dec;34(1):577-588. doi: 10.1080/14756366.2018.1558221. J Enzyme Inhib Med Chem. 2019. PMID: 30724629 Free PMC article.

9

The dipeptidyl peptidase-4 inhibitory effect of flavonoids is hindered in protein rich environments.

Proença C, Freitas M, Ribeiro D, Tomé SM, Araújo AN, Silva AMS, Fernandes PA, Fernandes E. Proença C, et al. Among authors: fernandes pa, fernandes e. Food Funct. 2019 Sep 1;10(9):5718-5731. doi: 10.1039/c9fo00722a. Epub 2019 Aug 23. Food Funct. 2019. PMID: 31441917

10

Anandamide targets aromatase: A breakthrough on human decidualization.

Almada M, Oliveira A, Amaral C, Fernandes PA, Ramos MJ, Fonseca B, Correia-da-Silva G, Teixeira N. Almada M, et al. Among authors: fernandes pa. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Dec;1864(12):158512. doi: 10.1016/j.bbalip.2019.08.008. Epub 2019 Aug 24. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31454668

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