Varrot A - Search Results

1

Cell-free expression and characterization of multivalent rhamnose-binding lectins using bio-layer interferometry.

Warfel KF, Laigre E, Sobol SE, Gillon E, Varrot A, Renaudet O, Dejeu J, Jewett MC, Imberty A. Warfel KF, et al. Among authors: varrot a. Glycobiology. 2023 Jun 3;33(5):358-363. doi: 10.1093/glycob/cwad018. Glycobiology. 2023. PMID: 36882003

2

Direct observation of the protonation state of an imino sugar glycosidase inhibitor upon binding.

Varrot A, Tarling CA, Macdonald JM, Stick RV, Zechel DL, Withers SG, Davies GJ. Varrot A, et al. J Am Chem Soc. 2003 Jun 25;125(25):7496-7. doi: 10.1021/ja034917k. J Am Chem Soc. 2003. PMID: 12812472

3

Structural basis for ligand binding and processivity in cellobiohydrolase Cel6A from Humicola insolens.

Varrot A, Frandsen TP, von Ossowski I, Boyer V, Cottaz S, Driguez H, Schülein M, Davies GJ. Varrot A, et al. Structure. 2003 Jul;11(7):855-64. doi: 10.1016/s0969-2126(03)00124-2. Structure. 2003. PMID: 12842048 Free article.

4

Structural changes of the active site tunnel of Humicola insolens cellobiohydrolase, Cel6A, upon oligosaccharide binding.

Varrot A, Schülein M, Davies GJ. Varrot A, et al. Biochemistry. 1999 Jul 13;38(28):8884-91. doi: 10.1021/bi9903998. Biochemistry. 1999. PMID: 10413461

Cellulases have traditionally been classified into cellobiohydrolases, which are effective in the degradation of crystalline materials, and endoglucanases, which appear to act on "soluble" regions of the substrate. Humicola insolensCel6A (CBH II) is a cellobiohydrolase fro …

Cellulases have traditionally been classified into cellobiohydrolases, which are effective in the degradation of crystalline materials, and …

5

NAD+ and metal-ion dependent hydrolysis by family 4 glycosidases: structural insight into specificity for phospho-beta-D-glucosides.

Varrot A, Yip VL, Li Y, Rajan SS, Yang X, Anderson WF, Thompson J, Withers SG, Davies GJ. Varrot A, et al. J Mol Biol. 2005 Feb 18;346(2):423-35. doi: 10.1016/j.jmb.2004.11.058. Epub 2005 Jan 7. J Mol Biol. 2005. PMID: 15670594

6

An unusual mechanism of glycoside hydrolysis involving redox and elimination steps by a family 4 beta-glycosidase from Thermotoga maritima.

Yip VL, Varrot A, Davies GJ, Rajan SS, Yang X, Thompson J, Anderson WF, Withers SG. Yip VL, et al. Among authors: varrot a. J Am Chem Soc. 2004 Jul 14;126(27):8354-5. doi: 10.1021/ja047632w. J Am Chem Soc. 2004. PMID: 15237973

7

Atomic resolution structure of endoglucanase Cel5A in complex with methyl 4,4II,4III,4IV-tetrathio-alpha-cellopentoside highlights the alternative binding modes targeted by substrate mimics.

Varrot A, Schülein M, Fruchard S, Driguez H, Davies GJ. Varrot A, et al. Acta Crystallogr D Biol Crystallogr. 2001 Nov;57(Pt 11):1739-42. doi: 10.1107/s0907444901013993. Epub 2001 Oct 25. Acta Crystallogr D Biol Crystallogr. 2001. PMID: 11679762

8

Mycobacterium tuberculosis strains possess functional cellulases.

Varrot A, Leydier S, Pell G, Macdonald JM, Stick RV, Henrissat B, Gilbert HJ, Davies GJ. Varrot A, et al. J Biol Chem. 2005 May 27;280(21):20181-4. doi: 10.1074/jbc.C500142200. Epub 2005 Apr 11. J Biol Chem. 2005. PMID: 15824123 Free article.

9

Direct experimental observation of the hydrogen-bonding network of a glycosidase along its reaction coordinate revealed by atomic resolution analyses of endoglucanase Cel5A.

Varrot A, Davies GJ. Varrot A, et al. Acta Crystallogr D Biol Crystallogr. 2003 Mar;59(Pt 3):447-52. doi: 10.1107/s0907444902023405. Epub 2003 Feb 21. Acta Crystallogr D Biol Crystallogr. 2003. PMID: 12595701

10

Mixed-linkage cellooligosaccharides: a new class of glycoside hydrolase inhibitors.

Fort S, Varrot A, Schülein M, Cottaz S, Driguez H, Davies GJ. Fort S, et al. Among authors: varrot a. Chembiochem. 2001 May 4;2(5):319-25. doi: 10.1002/1439-7633(20010504)2:5<319::AID-CBIC319>3.0.CO;2-Q. Chembiochem. 2001. PMID: 11828460

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