Ralphe JC - Search Results

1

cMyBP-C ablation in human engineered cardiac tissue causes progressive Ca2+-handling abnormalities.

De Lange WJ, Farrell ET, Hernandez JJ, Stempien A, Kreitzer CR, Jacobs DR, Petty DL, Moss RL, Crone WC, Ralphe JC. De Lange WJ, et al. Among authors: ralphe jc. J Gen Physiol. 2023 Apr 3;155(4):e202213204. doi: 10.1085/jgp.202213204. Epub 2023 Mar 9. J Gen Physiol. 2023. PMID: 36893011 Free PMC article.

2

Myocardial vascular and metabolic adaptations in chronically anemic fetal sheep.

Mascio CE, Olison AK, Ralphe JC, Tomanek RJ, Scholz TD, Segar JL. Mascio CE, et al. Among authors: ralphe jc. Am J Physiol Regul Integr Comp Physiol. 2005 Dec;289(6):R1736-45. doi: 10.1152/ajpregu.00278.2005. Epub 2005 Aug 25. Am J Physiol Regul Integr Comp Physiol. 2005. PMID: 16123231 Free article.

3

Correlation between myocardial malate/aspartate shuttle activity and EAAT1 protein expression in hyper- and hypothyroidism.

Ralphe JC, Bedell K, Segar JL, Scholz TD. Ralphe JC, et al. Am J Physiol Heart Circ Physiol. 2005 May;288(5):H2521-6. doi: 10.1152/ajpheart.00991.2004. Epub 2004 Dec 22. Am J Physiol Heart Circ Physiol. 2005. PMID: 15615843 Free article.

4

Metabolic adaptation of the fetal and postnatal ovine heart: regulatory role of hypoxia-inducible factors and nuclear respiratory factor-1.

Nau PN, Van Natta T, Ralphe JC, Teneyck CJ, Bedell KA, Caldarone CA, Segar JL, Scholz TD. Nau PN, et al. Among authors: ralphe jc. Pediatr Res. 2002 Aug;52(2):269-78. doi: 10.1203/00006450-200208000-00021. Pediatr Res. 2002. PMID: 12149506

5

Neonatal mouse-derived engineered cardiac tissue: a novel model system for studying genetic heart disease.

de Lange WJ, Hegge LF, Grimes AC, Tong CW, Brost TM, Moss RL, Ralphe JC. de Lange WJ, et al. Among authors: ralphe jc. Circ Res. 2011 Jun 24;109(1):8-19. doi: 10.1161/CIRCRESAHA.111.242354. Epub 2011 May 12. Circ Res. 2011. PMID: 21566213 Free PMC article.

6

Ablation of cardiac myosin-binding protein-C accelerates contractile kinetics in engineered cardiac tissue.

de Lange WJ, Grimes AC, Hegge LF, Ralphe JC. de Lange WJ, et al. Among authors: ralphe jc. J Gen Physiol. 2013 Jan;141(1):73-84. doi: 10.1085/jgp.201210837. J Gen Physiol. 2013. PMID: 23277475 Free PMC article.

7

3D engineered cardiac tissue models of human heart disease: learning more from our mice.

Ralphe JC, de Lange WJ. Ralphe JC, et al. Trends Cardiovasc Med. 2013 Feb;23(2):27-32. doi: 10.1016/j.tcm.2012.08.007. Epub 2013 Jan 5. Trends Cardiovasc Med. 2013. PMID: 23295081 Free PMC article. Review.

8

E258K HCM-causing mutation in cardiac MyBP-C reduces contractile force and accelerates twitch kinetics by disrupting the cMyBP-C and myosin S2 interaction.

De Lange WJ, Grimes AC, Hegge LF, Spring AM, Brost TM, Ralphe JC. De Lange WJ, et al. Among authors: ralphe jc. J Gen Physiol. 2013 Sep;142(3):241-55. doi: 10.1085/jgp.201311018. J Gen Physiol. 2013. PMID: 23980194 Free PMC article.

9

Pompe disease results in a Golgi-based glycosylation deficit in human induced pluripotent stem cell-derived cardiomyocytes.

Raval KK, Tao R, White BE, De Lange WJ, Koonce CH, Yu J, Kishnani PS, Thomson JA, Mosher DF, Ralphe JC, Kamp TJ. Raval KK, et al. Among authors: ralphe jc. J Biol Chem. 2015 Jan 30;290(5):3121-36. doi: 10.1074/jbc.M114.628628. Epub 2014 Dec 8. J Biol Chem. 2015. PMID: 25488666 Free PMC article.

10

Cardiac MyBP-C regulates the rate and force of contraction in mammalian myocardium.

Moss RL, Fitzsimons DP, Ralphe JC. Moss RL, et al. Among authors: ralphe jc. Circ Res. 2015 Jan 2;116(1):183-92. doi: 10.1161/CIRCRESAHA.116.300561. Circ Res. 2015. PMID: 25552695 Free PMC article. Review.

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