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BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma.
Feng Y, Cai L, Pook M, Liu F, Chang CH, Mouti MA, Nibhani R, Wu S, Deng S, Militi S, Dunford J, Philpott M, Fan Y, Fan GC, Liu Q, Qi J, Sadayappan S, Jegga AG, Oppermann U, Wang Y, Huang W, Jiang L, Pauklin S. Feng Y, et al. Among authors: qi j. bioRxiv [Preprint]. 2023 Mar 2:2023.03.02.530770. doi: 10.1101/2023.03.02.530770. bioRxiv. 2023. Update in: Gastroenterology. 2024 Jan;166(1):139-154. doi: 10.1053/j.gastro.2023.09.021 PMID: 36909530 Free PMC article. Updated. Preprint.
Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer.
Duplaquet L, So K, Ying AW, Li X, Li Y, Qiu X, Li R, Singh S, Wu XS, Liu Q, Qi J, Somerville TDD, Heiling H, Mazzola E, Lee Y, Zoller T, Vakoc CR, Doench JG, Forrester WC, Abrams T, Long HW, Niederst MJ, Kadoch C, Oser MG. Duplaquet L, et al. Among authors: qi j. bioRxiv [Preprint]. 2024 Jan 24:2024.01.21.576304. doi: 10.1101/2024.01.21.576304. bioRxiv. 2024. Update in: Cancer Cell. 2024 Aug 12;42(8):1352-1369.e13. doi: 10.1016/j.ccell.2024.06.012 PMID: 38328215 Free PMC article. Updated. Preprint.
Utilizing a dual endogenous reporter system to identify functional regulators of aberrant stem cell and differentiation activity in colorectal cancer.
Spisak S, Chen D, Likasitwatanakul P, Doan P, Li Z, Bala P, Vizkeleti L, Tisza V, De Silva P, Giannakis M, Wolpin B, Qi J, Sethi NS. Spisak S, et al. Among authors: qi j. bioRxiv [Preprint]. 2024 Jan 17:2023.06.21.545895. doi: 10.1101/2023.06.21.545895. bioRxiv. 2024. Update in: Nat Commun. 2024 Mar 12;15(1):2230. doi: 10.1038/s41467-024-46285-w PMID: 38293113 Free PMC article. Updated. Preprint.
SALL4B, not targeted by IMiD, is important for SALL4-mediated tumorigenesis.
L Vu KA, Kumari K, Liu BH, Gao C, Li F, Tang JP, Maddalo D, Auld DS, Casalena DE, Tian X, Liu M, Bassal MA, Moein S, Iakovleva V, Tan JL, Stein AJ, Zhou Q, Fischer PD, Sigua LH, Qi J, Arthanari H, Tenen DG, Chai L. L Vu KA, et al. Among authors: qi j. bioRxiv [Preprint]. 2023 Jul 7:2023.07.07.548071. doi: 10.1101/2023.07.07.548071. bioRxiv. 2023. PMID: 37461690 Free PMC article. Preprint.
Targeting transcription factors through an IMiD independent zinc finger domain.
Liu BH, Liu M, Radhakrishnan S, Jaladanki CK, Gao C, Tang JP, Kumari K, Go ML, Vu KAL, Seo HS, Song K, Tian X, Feng L, Tan JL, Bassal MA, Arthanari H, Qi J, Dhe-Paganon S, Fan H, Tenen DG, Chai L. Liu BH, et al. Among authors: qi j. bioRxiv [Preprint]. 2024 Jan 3:2024.01.03.574032. doi: 10.1101/2024.01.03.574032. bioRxiv. 2024. PMID: 38260640 Free PMC article. Preprint.
Exploration of the Tunability of BRD4 Degradation by DCAF16 Trans-labelling Covalent Glues.
Hassan MM, Li YD, Ma MW, Teng M, Byun WS, Puvar K, Lumpkin R, Sandoval B, Rutter JC, Jin CY, Wang MY, Xu S, Schmoker AM, Cheong H, Groendyke BJ, Qi J, Fischer ES, Ebert BL, Gray NS. Hassan MM, et al. Among authors: qi j. bioRxiv [Preprint]. 2023 Oct 10:2023.10.07.561308. doi: 10.1101/2023.10.07.561308. bioRxiv. 2023. Update in: Eur J Med Chem. 2024 Dec 5;279:116904. doi: 10.1016/j.ejmech.2024.116904 PMID: 37873358 Free PMC article. Updated. Preprint.
7,520 results