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51 results

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Page 1
Leveraging IFNγ/CD38 regulation to unmask and target leukemia stem cells in acute myelogenous leukemia.
Murtadha M, Park M, Zhu Y, Caserta E, Dona AA, Singer M, Vahed H, Tasndoh T, Gonzalez A, Ly K, Sanchez JF, Chowdhury A, Pozhitkov A, Ghoda L, Li L, Zhang B, Krishnan A, Marcucci G, Williams J, Pichiorri F. Murtadha M, et al. Among authors: ghoda l. bioRxiv [Preprint]. 2023 Mar 1:2023.02.27.530273. doi: 10.1101/2023.02.27.530273. bioRxiv. 2023. PMID: 36909542 Free PMC article. Preprint.
A CD38-directed, single-chain T-cell engager targets leukemia stem cells through IFN-γ-induced CD38 expression.
Murtadha M, Park M, Zhu Y, Caserta E, Napolitano O, Tandoh T, Moloudizargari M, Pozhitkov A, Singer M, Dona AA, Vahed H, Gonzalez A, Ly K, Ouyang C, Sanchez JF, Nigam L, Duplan A, Chowdhury A, Ghoda L, Li L, Zhang B, Krishnan A, Marcucci G, Williams JC, Pichiorri F. Murtadha M, et al. Among authors: ghoda l. Blood. 2024 Apr 18;143(16):1599-1615. doi: 10.1182/blood.2023021570. Blood. 2024. PMID: 38394668
Flotetuzumab as a salvage immunotherapy in advanced CD123-positive hematological malignancies, a phase 1 pilot study.
Aldoss I, Zhang J, Robbins M, Song J, Al Malki MM, Otoukesh S, Sandhu K, Agrawal V, Herrera AF, Popplewell LL, Ghoda L, Stein A, Marcucci G, Forman S, Pullarkat V. Aldoss I, et al. Among authors: ghoda l. Leuk Lymphoma. 2024 Aug;65(8):1127-1135. doi: 10.1080/10428194.2024.2343029. Epub 2024 Apr 17. Leuk Lymphoma. 2024. PMID: 38629176 Clinical Trial.
IL1RAP-specific T cell engager depletes acute myeloid leukemia stem cells.
Zhang Y, Park M, Ghoda LY, Zhao D, Valerio M, Nafie E, Gonzalez A, Ly K, Parcutela B, Choi H, Gong X, Chen F, Harada K, Chen Z, Nguyen LXT, Pichiorri F, Chen J, Song J, Forman SJ, Amanam I, Zhang B, Jin J, Williams JC, Marcucci G. Zhang Y, et al. Among authors: ghoda ly. J Hematol Oncol. 2024 Aug 14;17(1):67. doi: 10.1186/s13045-024-01586-x. J Hematol Oncol. 2024. PMID: 39143574 Free PMC article.
Homoharringtonine synergizes with venetoclax in early T cell progenitor acute lymphoblastic leukemia: Bench and bed.
Suo S, Sun S, Nguyen LXT, Qian J, Li F, Zhao D, Yu W, Lou Y, Zhu H, Tong H, Yang M, Huang X, Zhao S, Qiao J, Liang C, Wang H, Zhang Y, Zhang X, Hoang DH, Chen F, Kang H, Valerio M, Sun J, Ghoda L, Li L, Marcucci G, Zhang B, Jin J. Suo S, et al. Among authors: ghoda l. Med. 2024 Aug 10:S2666-6340(24)00300-3. doi: 10.1016/j.medj.2024.07.018. Online ahead of print. Med. 2024. PMID: 39151422
Venetoclax in combination with a pediatric-inspired regimen for the treatment of newly diagnosed adults with Philadelphia chromosome-negative acute lymphoblastic leukemia.
Aldoss I, Zhang J, Shimamoto K, Saygin C, Robbins M, Agrawal V, Aribi A, Karaoglu DA, Pourhassan H, Koller P, Ali H, Blackmon A, Otoukesh S, Sandhu K, Ball B, Artz AS, Al Malki MM, Salhotra A, Tinajero J, Gu Z, Lagman I, Velasquez M, Dang J, Becker PS, Afkhami M, Ghoda L, Stock W, Forman SJ, Stein A, Marcucci G, Pullarkat V. Aldoss I, et al. Among authors: ghoda l. Haematologica. 2024 Nov 7. doi: 10.3324/haematol.2024.286427. Online ahead of print. Haematologica. 2024. PMID: 39506897 Free article.
Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity.
Dong H, He X, Zhang L, Chen W, Lin YC, Liu SB, Wang H, Nguyen LXT, Li M, Zhu Y, Zhao D, Ghoda L, Serody J, Vincent B, Luznik L, Gojo I, Zeidner J, Su R, Chen J, Sharma R, Pirrotte P, Wu X, Hu W, Han W, Shen B, Kuo YH, Jin J, Salhotra A, Wang J, Marcucci G, Luo YL, Li L. Dong H, et al. Among authors: ghoda l. Nat Cancer. 2024 Apr;5(4):601-624. doi: 10.1038/s43018-024-00736-x. Epub 2024 Feb 27. Nat Cancer. 2024. PMID: 38413714 Free PMC article.
State-transition modeling of blood transcriptome predicts disease evolution and treatment response in chronic myeloid leukemia.
Frankhouser DE, Rockne RC, Uechi L, Zhao D, Branciamore S, O'Meally D, Irizarry J, Ghoda L, Ali H, Trent JM, Forman S, Fu YH, Kuo YH, Zhang B, Marcucci G. Frankhouser DE, et al. Among authors: ghoda l. Leukemia. 2024 Apr;38(4):769-780. doi: 10.1038/s41375-024-02142-9. Epub 2024 Feb 2. Leukemia. 2024. PMID: 38307941 Free PMC article.
51 results