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A comparative study of in vitro air-liquid interface culture models of the human airway epithelium evaluating cellular heterogeneity and gene expression at single cell resolution.
Prescott RA, Pankow AP, de Vries M, Crosse K, Patel RS, Alu M, Loomis C, Torres V, Koralov S, Ivanova E, Dittmann M, Rosenberg BR. Prescott RA, et al. bioRxiv [Preprint]. 2023 Feb 28:2023.02.27.530299. doi: 10.1101/2023.02.27.530299. bioRxiv. 2023. Update in: Respir Res. 2023 Aug 28;24(1):213. doi: 10.1186/s12931-023-02514-2 PMID: 36909601 Free PMC article. Updated. Preprint.
In-silico docking platform with serine protease inhibitor (SERPIN) structures identifies host cysteine protease targets with significance for SARS-CoV-2.
Rodriguez Galvan JJ, de Vries M, Belblidia S, Fisher A, Prescott RA, Crosse KM, Mangel WF, Duerr R, Dittmann M. Rodriguez Galvan JJ, et al. Among authors: prescott ra. bioRxiv [Preprint]. 2024 Mar 27:2022.11.18.517133. doi: 10.1101/2022.11.18.517133. bioRxiv. 2024. PMID: 36415456 Free PMC article. Preprint.
Genetic variation of staphylococcal LukAB toxin determines receptor tropism.
Perelman SS, James DBA, Boguslawski KM, Nelson CW, Ilmain JK, Zwack EE, Prescott RA, Mohamed A, Tam K, Chan R, Narechania A, Pawline MB, Vozhilla N, Moustafa AM, Kim SY, Dittmann M, Ekiert DC, Bhabha G, Shopsin B, Planet PJ, Koralov SB, Torres VJ. Perelman SS, et al. Among authors: prescott ra. Nat Microbiol. 2021 Jun;6(6):731-745. doi: 10.1038/s41564-021-00890-3. Epub 2021 Apr 19. Nat Microbiol. 2021. PMID: 33875847 Free PMC article.
A comparative analysis of SARS-CoV-2 antivirals characterizes 3CLpro inhibitor PF-00835231 as a potential new treatment for COVID-19.
de Vries M, Mohamed AS, Prescott RA, Valero-Jimenez AM, Desvignes L, O'Connor R, Steppan C, Devlin JC, Ivanova E, Herrera A, Schinlever A, Loose P, Ruggles K, Koralov SB, Anderson AS, Binder J, Dittmann M. de Vries M, et al. Among authors: prescott ra. J Virol. 2021 Mar 10;95(7):e01819-20. doi: 10.1128/JVI.01819-20. Epub 2021 Feb 23. J Virol. 2021. PMID: 33622961 Free PMC article.
A comparative analysis of SARS-CoV-2 antivirals in human airway models characterizes 3CLpro inhibitor PF-00835231 as a potential new treatment for COVID-19.
de Vries M, Mohamed AS, Prescott RA, Valero-Jimenez AM, Desvignes L, O'Connor R, Steppan C, Devlin JC, Ivanova E, Herrera A, Schinlever A, Loose P, Ruggles K, Koralov SB, Anderson AS, Binder J, Dittmann M. de Vries M, et al. Among authors: prescott ra. bioRxiv [Preprint]. 2021 Feb 19:2020.08.28.272880. doi: 10.1101/2020.08.28.272880. bioRxiv. 2021. Update in: J Virol. 2021 Feb 23;95(7):JVI.01819-20. doi: 10.1128/JVI.01819-20 PMID: 32869028 Free PMC article. Updated. Preprint.
The YrbE phospholipid transporter of Salmonella enterica serovar Typhi regulates the expression of flagellin and influences motility, adhesion and induction of epithelial inflammatory responses.
Verma S, Prescott RA, Ingano L, Nickerson KP, Hill E, Faherty CS, Fasano A, Senger S, Cherayil BJ. Verma S, et al. Among authors: prescott ra. Gut Microbes. 2020 May 3;11(3):526-538. doi: 10.1080/19490976.2019.1697593. Epub 2019 Dec 12. Gut Microbes. 2020. PMID: 31829769 Free PMC article.