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SOX17 Deficiency Mediates Pulmonary Hypertension: At the Crossroads of Sex, Metabolism, and Genetics.
Sangam S, Sun X, Schwantes-An TH, Yegambaram M, Lu Q, Shi Y, Cook T, Fisher A, Frump AL, Coleman A, Sun Y, Liang S, Crawford H, Lutz KA, Maun AD, Pauciulo MW, Karnes JH, Chaudhary KR, Stewart DJ, Langlais PR, Jain M, Alotaibi M, Lahm T, Jin Y, Gu H, Tang H, Nichols WC, Black SM, Desai AA. Sangam S, et al. Among authors: cook t. Am J Respir Crit Care Med. 2023 Apr 15;207(8):1055-1069. doi: 10.1164/rccm.202203-0450OC. Am J Respir Crit Care Med. 2023. PMID: 36913491 Free PMC article.
17β-Estradiol mediates superior adaptation of right ventricular function to acute strenuous exercise in female rats with severe pulmonary hypertension.
Lahm T, Frump AL, Albrecht ME, Fisher AJ, Cook TG, Jones TJ, Yakubov B, Whitson J, Fuchs RK, Liu A, Chesler NC, Brown MB. Lahm T, et al. Among authors: cook tg. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L375-88. doi: 10.1152/ajplung.00132.2016. Epub 2016 Jun 10. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27288487 Free PMC article.
Transcriptomic modifications in developmental cardiopulmonary adaptations to chronic hypoxia using a murine model of simulated high-altitude exposure.
Krishnan S, Stearman RS, Zeng L, Fisher A, Mickler EA, Rodriguez BH, Simpson ER, Cook T, Slaven JE, Ivan M, Geraci MW, Lahm T, Tepper RS. Krishnan S, et al. Among authors: cook t. Am J Physiol Lung Cell Mol Physiol. 2020 Sep 1;319(3):L456-L470. doi: 10.1152/ajplung.00487.2019. Epub 2020 Jul 8. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32639867 Free PMC article.
17β-Estradiol and estrogen receptor α protect right ventricular function in pulmonary hypertension via BMPR2 and apelin.
Frump AL, Albrecht M, Yakubov B, Breuils-Bonnet S, Nadeau V, Tremblay E, Potus F, Omura J, Cook T, Fisher A, Rodriguez B, Brown RD, Stenmark KR, Rubinstein CD, Krentz K, Tabima DM, Li R, Sun X, Chesler NC, Provencher S, Bonnet S, Lahm T. Frump AL, et al. Among authors: cook t. J Clin Invest. 2021 Mar 15;131(6):e129433. doi: 10.1172/JCI129433. J Clin Invest. 2021. PMID: 33497359 Free PMC article.
Skeletal Muscle SIRT3 Deficiency Contributes to Pulmonary Vascular Remodeling in Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction.
Jheng JR, Bai Y, Noda K, Huot JR, Cook T, Fisher A, Chen YY, Goncharov DA, Goncharova EA, Simon MA, Zhang Y, Forman DE, Rojas M, Machado RF, Auwerx J, Gladwin MT, Lai YC. Jheng JR, et al. Among authors: cook t. Circulation. 2024 Sep 10;150(11):867-883. doi: 10.1161/CIRCULATIONAHA.124.068624. Epub 2024 May 28. Circulation. 2024. PMID: 38804138
Plasma Proteomics Identifies B2M as a Regulator of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction.
Jheng JR, DesJardin JT, Chen YY, Huot JR, Bai Y, Cook T, Hibbard LM, Rupp JM, Fisher A, Zhang Y, Duarte JD, Desai AA, Machado RF, Simon MA, Lai YC. Jheng JR, et al. Among authors: cook t. Arterioscler Thromb Vasc Biol. 2024 Jul;44(7):1570-1583. doi: 10.1161/ATVBAHA.123.320270. Epub 2024 May 30. Arterioscler Thromb Vasc Biol. 2024. PMID: 38813697 Free PMC article.
Treatment With Treprostinil and Metformin Normalizes Hyperglycemia and Improves Cardiac Function in Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction.
Wang L, Halliday G, Huot JR, Satoh T, Baust JJ, Fisher A, Cook T, Hu J, Avolio T, Goncharov DA, Bai Y, Vanderpool RR, Considine RV, Bonetto A, Tan J, Bachman TN, Sebastiani A, McTiernan CF, Mora AL, Machado RF, Goncharova EA, Gladwin MT, Lai YC. Wang L, et al. Among authors: cook t. Arterioscler Thromb Vasc Biol. 2020 Jun;40(6):1543-1558. doi: 10.1161/ATVBAHA.119.313883. Epub 2020 Apr 9. Arterioscler Thromb Vasc Biol. 2020. PMID: 32268788 Free PMC article.
1,831 results