Becher B - Search Results

1

CD4⁺ T cells produce GM-CSF and drive immune-mediated glomerular disease by licensing monocyte-derived cells to produce MMP12.

Paust HJ, Song N, De Feo D, Asada N, Tuzlak S, Zhao Y, Riedel JH, Hellmig M, Sivayoganathan A, Peters A, Kaffke A, Borchers A, Wenzel UO, Steinmetz OM, Tiegs G, Meister E, Mack M, Kurts C, von Vietinghoff S, Lindenmeyer MT, Hoxha E, Stahl RAK, Huber TB, Bonn S, Meyer-Schwesinger C, Wiech T, Turner JE, Becher B, Krebs CF, Panzer U. Paust HJ, et al. Among authors: becher b. Sci Transl Med. 2023 Mar 15;15(687):eadd6137. doi: 10.1126/scitranslmed.add6137. Epub 2023 Mar 15. Sci Transl Med. 2023. PMID: 36921033

2

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

Codarri L, Gyülvészi G, Tosevski V, Hesske L, Fontana A, Magnenat L, Suter T, Becher B. Codarri L, et al. Among authors: becher b. Nat Immunol. 2011 Jun;12(6):560-7. doi: 10.1038/ni.2027. Epub 2011 Apr 24. Nat Immunol. 2011. PMID: 21516112

3

Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells.

Hartmann FJ, Khademi M, Aram J, Ammann S, Kockum I, Constantinescu C, Gran B, Piehl F, Olsson T, Codarri L, Becher B. Hartmann FJ, et al. Among authors: becher b. Nat Commun. 2014 Oct 3;5:5056. doi: 10.1038/ncomms6056. Nat Commun. 2014. PMID: 25278028 Free article.

4

The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity.

Croxford AL, Lanzinger M, Hartmann FJ, Schreiner B, Mair F, Pelczar P, Clausen BE, Jung S, Greter M, Becher B. Croxford AL, et al. Among authors: becher b. Immunity. 2015 Sep 15;43(3):502-14. doi: 10.1016/j.immuni.2015.08.010. Epub 2015 Sep 1. Immunity. 2015. PMID: 26341401 Free article.

5

GM-CSF in Neuroinflammation: Licensing Myeloid Cells for Tissue Damage.

Croxford AL, Spath S, Becher B. Croxford AL, et al. Among authors: becher b. Trends Immunol. 2015 Oct;36(10):651-662. doi: 10.1016/j.it.2015.08.004. Trends Immunol. 2015. PMID: 26431942 Review.

6

GM-CSF: From Growth Factor to Central Mediator of Tissue Inflammation.

Becher B, Tugues S, Greter M. Becher B, et al. Immunity. 2016 Nov 15;45(5):963-973. doi: 10.1016/j.immuni.2016.10.026. Immunity. 2016. PMID: 27851925 Free article. Review.

7

Dysregulation of the Cytokine GM-CSF Induces Spontaneous Phagocyte Invasion and Immunopathology in the Central Nervous System.

Spath S, Komuczki J, Hermann M, Pelczar P, Mair F, Schreiner B, Becher B. Spath S, et al. Among authors: becher b. Immunity. 2017 Feb 21;46(2):245-260. doi: 10.1016/j.immuni.2017.01.007. Immunity. 2017. PMID: 28228281 Free article.

8

The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes.

Anzai A, Choi JL, He S, Fenn AM, Nairz M, Rattik S, McAlpine CS, Mindur JE, Chan CT, Iwamoto Y, Tricot B, Wojtkiewicz GR, Weissleder R, Libby P, Nahrendorf M, Stone JR, Becher B, Swirski FK. Anzai A, et al. Among authors: becher b. J Exp Med. 2017 Nov 6;214(11):3293-3310. doi: 10.1084/jem.20170689. Epub 2017 Oct 4. J Exp Med. 2017. PMID: 28978634 Free PMC article.

9

IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression.

Casella G, Finardi A, Descamps H, Colombo F, Maiorino C, Ruffini F, Patrone M, Degano M, Martino G, Muzio L, Becher B, Furlan R. Casella G, et al. Among authors: becher b. Sci Rep. 2017 Nov 29;7(1):16547. doi: 10.1038/s41598-017-16702-w. Sci Rep. 2017. PMID: 29185463 Free PMC article.

10

Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF-licensed myeloid cells.

Tugues S, Amorim A, Spath S, Martin-Blondel G, Schreiner B, De Feo D, Lutz M, Guscetti F, Apostolova P, Haftmann C, Hasselblatt P, Núñez NG, Hottiger MO, van den Broek M, Manz MG, Zeiser R, Becher B. Tugues S, et al. Among authors: becher b. Sci Transl Med. 2018 Nov 28;10(469):eaat8410. doi: 10.1126/scitranslmed.aat8410. Sci Transl Med. 2018. PMID: 30487251

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