Lindholm P - Search Results

1

CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress.

De Lorenzo F, Lüningschrör P, Nam J, Beckett L, Pilotto F, Galli E, Lindholm P, Rüdt von Collenberg C, Mungwa ST, Jablonka S, Kauder J, Thau-Habermann N, Petri S, Lindholm D, Saxena S, Sendtner M, Saarma M, Voutilainen MH. De Lorenzo F, et al. Among authors: lindholm d, lindholm p. Brain. 2023 Sep 1;146(9):3783-3799. doi: 10.1093/brain/awad087. Brain. 2023. PMID: 36928391 Free PMC article.

2

A novel human processed gene, DAD-R, maps to 12p12 and is expressed in several organs.

Kuittinen T, Eggert A, Lindholm P, Horelli-Kuitunen N, Palotie A, Maris JM, Saarma M. Kuittinen T, et al. Among authors: lindholm p. FEBS Lett. 2000 May 12;473(2):233-6. doi: 10.1016/s0014-5793(00)01358-2. FEBS Lett. 2000. PMID: 10812081 Free article.

3

PSPN/GFRalpha4 has a significantly weaker capacity than GDNF/GFRalpha1 to recruit RET to rafts, but promotes neuronal survival and neurite outgrowth.

Yang J, Lindahl M, Lindholm P, Virtanen H, Coffey E, Runeberg-Roos P, Saarma M. Yang J, et al. Among authors: lindholm p. FEBS Lett. 2004 Jul 2;569(1-3):267-71. doi: 10.1016/j.febslet.2004.06.007. FEBS Lett. 2004. PMID: 15225646 Free article.

4

Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo.

Lindholm P, Voutilainen MH, Laurén J, Peränen J, Leppänen VM, Andressoo JO, Lindahl M, Janhunen S, Kalkkinen N, Timmusk T, Tuominen RK, Saarma M. Lindholm P, et al. Nature. 2007 Jul 5;448(7149):73-7. doi: 10.1038/nature05957. Nature. 2007. PMID: 17611540

5

MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain.

Lindholm P, Peränen J, Andressoo JO, Kalkkinen N, Kokaia Z, Lindvall O, Timmusk T, Saarma M. Lindholm P, et al. Mol Cell Neurosci. 2008 Nov;39(3):356-71. doi: 10.1016/j.mcn.2008.07.016. Epub 2008 Jul 30. Mol Cell Neurosci. 2008. PMID: 18718866

6

The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional.

Parkash V, Lindholm P, Peränen J, Kalkkinen N, Oksanen E, Saarma M, Leppänen VM, Goldman A. Parkash V, et al. Among authors: lindholm p. Protein Eng Des Sel. 2009 Apr;22(4):233-41. doi: 10.1093/protein/gzn080. Epub 2009 Mar 3. Protein Eng Des Sel. 2009. PMID: 19258449

7

Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's disease.

Voutilainen MH, Bäck S, Pörsti E, Toppinen L, Lindgren L, Lindholm P, Peränen J, Saarma M, Tuominen RK. Voutilainen MH, et al. Among authors: lindholm p. J Neurosci. 2009 Jul 29;29(30):9651-9. doi: 10.1523/JNEUROSCI.0833-09.2009. J Neurosci. 2009. PMID: 19641128 Free PMC article.

8

Novel CDNF/MANF family of neurotrophic factors.

Lindholm P, Saarma M. Lindholm P, et al. Dev Neurobiol. 2010 Apr;70(5):360-71. doi: 10.1002/dneu.20760. Dev Neurobiol. 2010. PMID: 20186704 Review.

9

Mesencephalic astrocyte-derived neurotrophic factor (MANF) has a unique mechanism to rescue apoptotic neurons.

Hellman M, Arumäe U, Yu LY, Lindholm P, Peränen J, Saarma M, Permi P. Hellman M, et al. Among authors: lindholm p. J Biol Chem. 2011 Jan 28;286(4):2675-80. doi: 10.1074/jbc.M110.146738. Epub 2010 Nov 3. J Biol Chem. 2011. PMID: 21047780 Free PMC article.

10

Chronic infusion of CDNF prevents 6-OHDA-induced deficits in a rat model of Parkinson's disease.

Voutilainen MH, Bäck S, Peränen J, Lindholm P, Raasmaja A, Männistö PT, Saarma M, Tuominen RK. Voutilainen MH, et al. Among authors: lindholm p. Exp Neurol. 2011 Mar;228(1):99-108. doi: 10.1016/j.expneurol.2010.12.013. Epub 2010 Dec 24. Exp Neurol. 2011. PMID: 21185834

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