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CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress.
De Lorenzo F, Lüningschrör P, Nam J, Beckett L, Pilotto F, Galli E, Lindholm P, Rüdt von Collenberg C, Mungwa ST, Jablonka S, Kauder J, Thau-Habermann N, Petri S, Lindholm D, Saxena S, Sendtner M, Saarma M, Voutilainen MH. De Lorenzo F, et al. Among authors: voutilainen mh. Brain. 2023 Sep 1;146(9):3783-3799. doi: 10.1093/brain/awad087. Brain. 2023. PMID: 36928391 Free PMC article.
CNPY2 protects against ER stress and is expressed by corticostriatal neurons together with CTIP2 in a mouse model of Huntington's disease.
Scordino M, Stepanova P, Srinivasan V, Pham DD, Eriksson O, Lalowski M, Mudò G, Di Liberto V, Korhonen L, Voutilainen MH, Lindholm D. Scordino M, et al. Among authors: voutilainen mh. Front Mol Neurosci. 2024 Sep 18;17:1473058. doi: 10.3389/fnmol.2024.1473058. eCollection 2024. Front Mol Neurosci. 2024. PMID: 39359687 Free PMC article.
MANF regulates neuronal survival and UPR through its ER-located receptor IRE1α.
Kovaleva V, Yu LY, Ivanova L, Shpironok O, Nam J, Eesmaa A, Kumpula EP, Sakson S, Toots U, Ustav M, Huiskonen JT, Voutilainen MH, Lindholm P, Karelson M, Saarma M. Kovaleva V, et al. Among authors: voutilainen mh. Cell Rep. 2023 Feb 28;42(2):112066. doi: 10.1016/j.celrep.2023.112066. Epub 2023 Feb 3. Cell Rep. 2023. PMID: 36739529 Free article.
39 results