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Page 1
Regulatory architecture of housekeeping genes is driven by promoter assemblies.
Dejosez M, Dall'Agnese A, Ramamoorthy M, Platt J, Yin X, Hogan M, Brosh R, Weintraub AS, Hnisz D, Abraham BJ, Young RA, Zwaka TP. Dejosez M, et al. Among authors: brosh r. Cell Rep. 2023 May 30;42(5):112505. doi: 10.1016/j.celrep.2023.112505. Epub 2023 May 12. Cell Rep. 2023. PMID: 37182209 Free PMC article.
Genomic context sensitizes regulatory elements to genetic disruption.
Ordoñez R, Zhang W, Ellis G, Zhu Y, Ashe HJ, Ribeiro-Dos-Santos AM, Brosh R, Huang E, Hogan MS, Boeke JD, Maurano MT. Ordoñez R, et al. Among authors: brosh r. bioRxiv [Preprint]. 2024 Mar 12:2023.07.02.547201. doi: 10.1101/2023.07.02.547201. bioRxiv. 2024. Update in: Mol Cell. 2024 May 16;84(10):1842-1854.e7. doi: 10.1016/j.molcel.2024.04.013 PMID: 37781588 Free PMC article. Updated. Preprint.
Genomic context sensitizes regulatory elements to genetic disruption.
Ordoñez R, Zhang W, Ellis G, Zhu Y, Ashe HJ, Ribeiro-Dos-Santos AM, Brosh R, Huang E, Hogan MS, Boeke JD, Maurano MT. Ordoñez R, et al. Among authors: brosh r. Mol Cell. 2024 May 16;84(10):1842-1854.e7. doi: 10.1016/j.molcel.2024.04.013. Mol Cell. 2024. PMID: 38759624
Replication stress as a driver of cellular senescence and aging.
Herr LM, Schaffer ED, Fuchs KF, Datta A, Brosh RM Jr. Herr LM, et al. Among authors: brosh rm jr. Commun Biol. 2024 May 22;7(1):616. doi: 10.1038/s42003-024-06263-w. Commun Biol. 2024. PMID: 38777831 Free PMC article. Review.
Synthetic reversed sequences reveal default genomic states.
Camellato BR, Brosh R, Ashe HJ, Maurano MT, Boeke JD. Camellato BR, et al. Among authors: brosh r. Nature. 2024 Apr;628(8007):373-380. doi: 10.1038/s41586-024-07128-2. Epub 2024 Mar 6. Nature. 2024. PMID: 38448583 Free PMC article.
On the genetic basis of tail-loss evolution in humans and apes.
Xia B, Zhang W, Zhao G, Zhang X, Bai J, Brosh R, Wudzinska A, Huang E, Ashe H, Ellis G, Pour M, Zhao Y, Coelho C, Zhu Y, Miller A, Dasen JS, Maurano MT, Kim SY, Boeke JD, Yanai I. Xia B, et al. Among authors: brosh r. Nature. 2024 Feb;626(8001):1042-1048. doi: 10.1038/s41586-024-07095-8. Epub 2024 Feb 28. Nature. 2024. PMID: 38418917 Free PMC article.
Editorial: DNA repair and interventions in aging.
Brosh RM Jr, Moskalev A, Gorbunova V. Brosh RM Jr, et al. Front Aging. 2023 Dec 5;4:1306463. doi: 10.3389/fragi.2023.1306463. eCollection 2023. Front Aging. 2023. PMID: 38115889 Free PMC article. No abstract available.
230 results