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Blocking Dectin-1 prevents colorectal tumorigenesis by suppressing prostaglandin E2 production in myeloid-derived suppressor cells and enhancing IL-22 binding protein expression.
Tang C, Sun H, Kadoki M, Han W, Ye X, Makusheva Y, Deng J, Feng B, Qiu D, Tan Y, Wang X, Guo Z, Huang C, Peng S, Chen M, Adachi Y, Ohno N, Trombetta S, Iwakura Y. Tang C, et al. Among authors: wang x. Nat Commun. 2023 Mar 17;14(1):1493. doi: 10.1038/s41467-023-37229-x. Nat Commun. 2023. PMID: 36932082 Free PMC article.
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