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Page 1
Sublethal necroptosis signaling promotes inflammation and liver cancer.
Vucur M, Ghallab A, Schneider AT, Adili A, Cheng M, Castoldi M, Singer MT, Büttner V, Keysberg LS, Küsgens L, Kohlhepp M, Görg B, Gallage S, Barragan Avila JE, Unger K, Kordes C, Leblond AL, Albrecht W, Loosen SH, Lohr C, Jördens MS, Babler A, Hayat S, Schumacher D, Koenen MT, Govaere O, Boekschoten MV, Jörs S, Villacorta-Martin C, Mazzaferro V, Llovet JM, Weiskirchen R, Kather JN, Starlinger P, Trauner M, Luedde M, Heij LR, Neumann UP, Keitel V, Bode JG, Schneider RK, Tacke F, Levkau B, Lammers T, Fluegen G, Alexandrov T, Collins AL, Nelson G, Oakley F, Mann DA, Roderburg C, Longerich T, Weber A, Villanueva A, Samson AL, Murphy JM, Kramann R, Geisler F, Costa IG, Hengstler JG, Heikenwalder M, Luedde T. Vucur M, et al. Among authors: heikenwalder m. Immunity. 2023 Jul 11;56(7):1578-1595.e8. doi: 10.1016/j.immuni.2023.05.017. Epub 2023 Jun 16. Immunity. 2023. PMID: 37329888 Free article.
Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironment.
Roehlen N, Muller M, Nehme Z, Crouchet E, Jühling F, Del Zompo F, Cherradi S, Duong FHT, Almeida N, Saviano A, Fernández-Vaquero M, Riedl T, El Saghire H, Durand SC, Ponsolles C, Oudot MA, Martin R, Brignon N, Felli E, Pessaux P, Lallement A, Davidson I, Bandiera S, Thumann C, Marchand P, Moll S, Nicolay B, Bardeesy N, Hoshida Y, Heikenwälder M, Iacone R, Toso A, Meyer M, Elson G, Schweighoffer T, Teixeira G, Zeisel MB, Laquerriere P, Lupberger J, Schuster C, Mailly L, Baumert TF. Roehlen N, et al. Among authors: heikenwalder m. J Hepatol. 2023 Feb;78(2):343-355. doi: 10.1016/j.jhep.2022.10.011. Epub 2022 Oct 27. J Hepatol. 2023. PMID: 36309131 Free article.
Etiology-independent activation of the LTβ-LTβR-RELB axis drives aggressiveness and predicts poor prognosis in HCC.
Scherr AL, Nader L, Xu K, Elssner C, Ridder DA, Nichetti F, Mastel M, Fritzsche S, Kelmendi E, Schmitt N, Hoffmeister-Wittmann P, Weiler SME, Korell F, Albrecht T, Schwab M, Isele H, Kessler A, Hüllein J, Seretny A, Ye L, Urbanik T, Welte S, Leblond AL, Heilig CE, Rahbari M, Ali A, Gallage S, Lenoir B, Wilhelm N, Gärtner U, Ogrodnik SJ, Springfeld C, Tschaharganeh D, Fröhling S, Longerich T, Schulze-Bergkamen H, Jäger D, Brandl L, Schirmacher P, Straub BK, Weber A, De Toni EN, Goeppert B, Heikenwalder M, Jackstadt R, Roessler S, Breuhahn K, Köhler BC. Scherr AL, et al. Among authors: heikenwalder m. Hepatology. 2024 Aug 1;80(2):278-294. doi: 10.1097/HEP.0000000000000657. Epub 2023 Nov 2. Hepatology. 2024. PMID: 37916976
Intermittent fasting-the future treatment in NASH patients?
Minciuna I, Gallage S, Heikenwalder M, Zelber-Sagi S, Dufour JF. Minciuna I, et al. Among authors: heikenwalder m. Hepatology. 2023 Oct 1;78(4):1290-1305. doi: 10.1097/HEP.0000000000000330. Epub 2023 Apr 17. Hepatology. 2023. PMID: 37057877 Review.
Spatially Resolved Multi-Omics Single-Cell Analyses Inform Mechanisms of Immune Dysfunction in Pancreatic Cancer.
Yousuf S, Qiu M, Voith von Voithenberg L, Hulkkonen J, Macinkovic I, Schulz AR, Hartmann D, Mueller F, Mijatovic M, Ibberson D, AlHalabi KT, Hetzer J, Anders S, Brüne B, Mei HE, Imbusch CD, Brors B, Heikenwälder M, Gaida MM, Büchler MW, Weigert A, Hackert T, Roth S. Yousuf S, et al. Among authors: heikenwalder m. Gastroenterology. 2023 Oct;165(4):891-908.e14. doi: 10.1053/j.gastro.2023.05.036. Epub 2023 May 30. Gastroenterology. 2023. PMID: 37263303 Free article.
Corrigendum to "Comparison of HAV and HCV infections in vivo and in vitro reveals distinct patterns of innate immune evasion and activation" [J Hepatol (2023) 645-656].
Colasanti O, Burm R, Huang HE, Riedl T, Traut J, Gillich N, Li TF, Corneillie L, Faure-Dupuy S, Grünvogel O, Heide D, Lee JY, Tran CS, Merle U, Chironna M, Vondran FFW, Esser-Nobis K, Binder M, Bartenschlager R, Heikenwälder M, Meuleman P, Lohmann V. Colasanti O, et al. Among authors: heikenwalder m. J Hepatol. 2024 Jan;80(1):171-172. doi: 10.1016/j.jhep.2023.11.007. Epub 2023 Nov 30. J Hepatol. 2024. PMID: 38040570 Free article. No abstract available.
Targeting the liver clock improves fibrosis by restoring TGF-β signaling.
Crouchet E, Dachraoui M, Jühling F, Roehlen N, Oudot MA, Durand SC, Ponsolles C, Gadenne C, Meiss-Heydmann L, Moehlin J, Martin R, Brignon N, Del Zompo F, Teraoka Y, Aikata H, Abe-Chayama H, Chayama K, Saviano A, Heide D, Onea M, Geyer L, Wolf T, Felli E, Pessaux P, Heikenwälder M, Chambon P, Schuster C, Lupberger J, Mukherji A, Baumert TF. Crouchet E, et al. Among authors: heikenwalder m. J Hepatol. 2024 Aug 22:S0168-8278(24)02480-2. doi: 10.1016/j.jhep.2024.07.034. Online ahead of print. J Hepatol. 2024. PMID: 39173955
343 results