Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation.
Kremer-Tal S, Narla G, Chen Y, Hod E, DiFeo A, Yea S, Lee JS, Schwartz M, Thung SN, Fiel IM, Banck M, Zimran E, Thorgeirsson SS, Mazzaferro V, Bruix J, Martignetti JA, Llovet JM, Friedman SL.
Kremer-Tal S, et al. Among authors: llovet jm.
J Hepatol. 2007 Apr;46(4):645-54. doi: 10.1016/j.jhep.2006.10.012. Epub 2006 Nov 27.
J Hepatol. 2007.
PMID: 17196295
Free PMC article.