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mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy.
Olivera I, Bolaños E, Gonzalez-Gomariz J, Hervas-Stubbs S, Mariño KV, Luri-Rey C, Etxeberria I, Cirella A, Egea J, Glez-Vaz J, Garasa S, Alvarez M, Eguren-Santamaria I, Guedan S, Sanmamed MF, Berraondo P, Rabinovich GA, Teijeira A, Melero I. Olivera I, et al. Among authors: alvarez m. Cell Rep Med. 2023 Mar 17;4(3):100978. doi: 10.1016/j.xcrm.2023.100978. Online ahead of print. Cell Rep Med. 2023. PMID: 36933554 Free PMC article.
Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy.
Perez-Ruiz E, Minute L, Otano I, Alvarez M, Ochoa MC, Belsue V, de Andrea C, Rodriguez-Ruiz ME, Perez-Gracia JL, Marquez-Rodas I, Llacer C, Alvarez M, de Luque V, Molina C, Teijeira A, Berraondo P, Melero I. Perez-Ruiz E, et al. Among authors: alvarez m. Nature. 2019 May;569(7756):428-432. doi: 10.1038/s41586-019-1162-y. Epub 2019 May 1. Nature. 2019. PMID: 31043740 Free article.
Repurposing the yellow fever vaccine for intratumoral immunotherapy.
Aznar MA, Molina C, Teijeira A, Rodriguez I, Azpilikueta A, Garasa S, Sanchez-Paulete AR, Cordeiro L, Etxeberria I, Alvarez M, Rius-Rocabert S, Nistal-Villan E, Berraondo P, Melero I. Aznar MA, et al. Among authors: alvarez m. EMBO Mol Med. 2020 Jan 9;12(1):e10375. doi: 10.15252/emmm.201910375. Epub 2019 Nov 19. EMBO Mol Med. 2020. PMID: 31746149 Free PMC article.
Premortem Tumor Stress in Radioimmunotherapy.
Melero I, Alvarez M, Minute L, Berraondo P. Melero I, et al. Among authors: alvarez m. Trends Cancer. 2020 Mar;6(3):173-174. doi: 10.1016/j.trecan.2020.01.001. Epub 2020 Jan 27. Trends Cancer. 2020. PMID: 32101719
Cellular cytotoxicity is a form of immunogenic cell death.
Minute L, Teijeira A, Sanchez-Paulete AR, Ochoa MC, Alvarez M, Otano I, Etxeberrria I, Bolaños E, Azpilikueta A, Garasa S, Casares N, Perez Gracia JL, Rodriguez-Ruiz ME, Berraondo P, Melero I. Minute L, et al. Among authors: alvarez m. J Immunother Cancer. 2020 Mar;8(1):e000325. doi: 10.1136/jitc-2019-000325. J Immunother Cancer. 2020. PMID: 32217765 Free PMC article.
Human CD8 T cells are susceptible to TNF-mediated activation-induced cell death.
Otano I, Alvarez M, Minute L, Ochoa MC, Migueliz I, Molina C, Azpilikueta A, de Andrea CE, Etxeberria I, Sanmamed MF, Teijeira Á, Berraondo P, Melero I. Otano I, et al. Among authors: alvarez m. Theranostics. 2020 Mar 15;10(10):4481-4489. doi: 10.7150/thno.41646. eCollection 2020. Theranostics. 2020. PMID: 32292509 Free PMC article.
3,858 results