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Page 1
Efficacy of LCMV-based cancer immunotherapies is unleashed by intratumoral injections of polyI:C.
Gomar C, Di Trani CA, Bella A, Arrizabalaga L, Gonzalez-Gomariz J, Fernandez-Sendin M, Alvarez M, Russo-Cabrera JS, Ardaiz N, Aranda F, Schippers T, Quintero M, Melero I, Orlinger KK, Lauterbach H, Berraondo P. Gomar C, et al. Among authors: gonzalez gomariz j. J Immunother Cancer. 2024 Apr 16;12(4):e008287. doi: 10.1136/jitc-2023-008287. J Immunother Cancer. 2024. PMID: 38631714 Free PMC article.
Intraperitoneal administration of a modified vaccinia virus Ankara confers single-chain interleukin-12 expression to the omentum and achieves immune-mediated efficacy against peritoneal carcinomatosis.
Bella Á, Arrizabalaga L, Di Trani CA, Gonzalez-Gomariz J, Gomar C, Russo-Cabrera JS, Olivera I, Cirella A, Fernandez-Sendin M, Alvarez M, Teijeira A, Atay C, Medina-Echeverz J, Hinterberger M, Hochrein H, Melero I, Berraondo P, Aranda F. Bella Á, et al. Among authors: gonzalez gomariz j. J Immunother Cancer. 2023 Nov;11(11):e006702. doi: 10.1136/jitc-2023-006702. J Immunother Cancer. 2023. PMID: 37918917 Free PMC article.
Intratumoral injection of IL-12-encoding mRNA targeted to CSFR1 and PD-L1 exerts potent anti-tumor effects without substantial systemic exposure.
Di Trani CA, Cirella A, Arrizabalaga L, Alvarez M, Bella Á, Fernandez-Sendin M, Russo-Cabrera JS, Gomar C, Ardaiz N, Teijeira A, Bolaños E, González-Gomariz J, Otano I, Aranda F, Palencia B, Segués A, Huang S, van Duijnhoven SMJ, van Elsas A, Melero I, Berraondo P. Di Trani CA, et al. Among authors: gonzalez gomariz j. Mol Ther Nucleic Acids. 2023 Jul 19;33:599-616. doi: 10.1016/j.omtn.2023.07.020. eCollection 2023 Sep 12. Mol Ther Nucleic Acids. 2023. PMID: 37637207 Free PMC article.
Intratumoral neoadjuvant immunotherapy based on the BO-112 viral RNA mimetic.
Alvarez M, Molina C, Garasa S, Ochoa MC, Rodriguez-Ruiz ME, Gomis G, Cirella A, Olivera I, Glez-Vaz J, Gonzalez-Gomariz J, Luri-Rey C, Azpilikueta A, Bolaños E, Teijeira A, Berraondo P, Quintero M, Melero I. Alvarez M, et al. Among authors: gonzalez gomariz j. Oncoimmunology. 2023 Apr 5;12(1):2197370. doi: 10.1080/2162402X.2023.2197370. eCollection 2023. Oncoimmunology. 2023. PMID: 37035637 Free PMC article.
mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy.
Olivera I, Bolaños E, Gonzalez-Gomariz J, Hervas-Stubbs S, Mariño KV, Luri-Rey C, Etxeberria I, Cirella A, Egea J, Glez-Vaz J, Garasa S, Alvarez M, Eguren-Santamaria I, Guedan S, Sanmamed MF, Berraondo P, Rabinovich GA, Teijeira A, Melero I. Olivera I, et al. Among authors: gonzalez gomariz j. Cell Rep Med. 2023 Mar 17;4(3):100978. doi: 10.1016/j.xcrm.2023.100978. Online ahead of print. Cell Rep Med. 2023. PMID: 36933554 Free PMC article.
Intracavitary adoptive transfer of IL-12 mRNA-engineered tumor-specific CD8+ T cells eradicates peritoneal metastases in mouse models.
Di Trani CA, Cirella A, Arrizabalaga L, Bella Á, Fernandez-Sendin M, Russo-Cabrera JS, Gomar C, Olivera I, Bolaños E, González-Gomariz J, Álvarez M, Etxeberria I, Palencia B, Teijeira Á, Melero I, Berraondo P, Aranda F. Di Trani CA, et al. Among authors: gonzalez gomariz j. Oncoimmunology. 2022 Dec 15;12(1):2147317. doi: 10.1080/2162402X.2022.2147317. eCollection 2023. Oncoimmunology. 2022. PMID: 36531687 Free PMC article.
Intratumoral Gene Transfer of mRNAs Encoding IL12 in Combination with Decoy-Resistant IL18 Improves Local and Systemic Antitumor Immunity.
Cirella A, Bolaños E, Di Trani CA, de Andrea CE, Sánchez-Gregorio S, Etxeberria I, Gonzalez-Gomariz J, Olivera I, Brocco D, Glez-Vaz J, Luri-Rey C, Azpilikueta A, Rodríguez I, Fernandez-Sendín M, Egea J, Eguren I, Sanmamed MF, Palencia B, Teijeira A, Berraondo P, Melero I. Cirella A, et al. Among authors: gonzalez gomariz j. Cancer Immunol Res. 2023 Feb 3;11(2):184-198. doi: 10.1158/2326-6066.CIR-22-0373. Cancer Immunol Res. 2023. PMID: 36478221 Free article.
Synergistic antitumor response with recombinant modified virus Ankara armed with CD40L and CD137L against peritoneal carcinomatosis.
Bella Á, Arrizabalaga L, Di Trani CA, Cirella A, Fernandez-Sendin M, Gomar C, Russo-Cabrera JS, Rodríguez I, González-Gomariz J, Alvarez M, Teijeira Á, Medina-Echeverz J, Hinterberger M, Hochrein H, Melero I, Berraondo P, Aranda F. Bella Á, et al. Among authors: gonzalez gomariz j. Oncoimmunology. 2022 Jul 13;11(1):2098657. doi: 10.1080/2162402X.2022.2098657. eCollection 2022. Oncoimmunology. 2022. PMID: 35859732 Free PMC article.
Intratumoral co-injection of the poly I:C-derivative BO-112 and a STING agonist synergize to achieve local and distant anti-tumor efficacy.
Alvarez M, Molina C, De Andrea CE, Fernandez-Sendin M, Villalba M, Gonzalez-Gomariz J, Ochoa MC, Teijeira A, Glez-Vaz J, Aranda F, Sanmamed MF, Rodriguez-Ruiz ME, Fan X, Shen WH, Berraondo P, Quintero M, Melero I. Alvarez M, et al. Among authors: gonzalez gomariz j. J Immunother Cancer. 2021 Nov;9(11):e002953. doi: 10.1136/jitc-2021-002953. J Immunother Cancer. 2021. PMID: 34824158 Free PMC article.
11 results