Haapanen O - Search Results

1

Structural basis of mitochondrial membrane bending by the I-II-III₂-IV₂ supercomplex.

Mühleip A, Flygaard RK, Baradaran R, Haapanen O, Gruhl T, Tobiasson V, Maréchal A, Sharma V, Amunts A. Mühleip A, et al. Among authors: haapanen o. Nature. 2023 Mar;615(7954):934-938. doi: 10.1038/s41586-023-05817-y. Epub 2023 Mar 22. Nature. 2023. PMID: 36949187 Free PMC article.

2

Tunnel dynamics of quinone derivatives and its coupling to protein conformational rearrangements in respiratory complex I.

Lasham J, Haapanen O, Zickermann V, Sharma V. Lasham J, et al. Among authors: haapanen o. Biochim Biophys Acta Bioenerg. 2023 Apr 1;1864(2):148951. doi: 10.1016/j.bbabio.2022.148951. Epub 2022 Dec 9. Biochim Biophys Acta Bioenerg. 2023. PMID: 36509126 Free article.

3

Ion transfer mechanisms in Mrp-type antiporters from high resolution cryoEM and molecular dynamics simulations.

Lee Y, Haapanen O, Altmeyer A, Kühlbrandt W, Sharma V, Zickermann V. Lee Y, et al. Among authors: haapanen o. Nat Commun. 2022 Oct 14;13(1):6091. doi: 10.1038/s41467-022-33640-y. Nat Commun. 2022. PMID: 36241630 Free PMC article.

4

Unexpected structures formed by the kinase RET C634R mutant extracellular domain suggest potential oncogenic mechanisms in MEN2A.

Liu Y, De Castro Ribeiro O, Haapanen O, Craven GB, Sharma V, Muench SP, Goldman A. Liu Y, et al. Among authors: haapanen o. J Biol Chem. 2022 Oct;298(10):102380. doi: 10.1016/j.jbc.2022.102380. Epub 2022 Aug 17. J Biol Chem. 2022. PMID: 35985422 Free PMC article.

5

Docking and molecular simulations reveal a quinone-binding site on the surface of respiratory complex I.

Djurabekova A, Galemou Yoga E, Nyman A, Pirttikoski A, Zickermann V, Haapanen O, Sharma V. Djurabekova A, et al. Among authors: haapanen o. FEBS Lett. 2022 May;596(9):1133-1146. doi: 10.1002/1873-3468.14346. Epub 2022 Apr 17. FEBS Lett. 2022. PMID: 35363885 Free article.

6

High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism.

Parey K, Lasham J, Mills DJ, Djurabekova A, Haapanen O, Yoga EG, Xie H, Kühlbrandt W, Sharma V, Vonck J, Zickermann V. Parey K, et al. Among authors: haapanen o. Sci Adv. 2021 Nov 12;7(46):eabj3221. doi: 10.1126/sciadv.abj3221. Epub 2021 Nov 12. Sci Adv. 2021. PMID: 34767441 Free PMC article.

7

Essential role of accessory subunit LYRM6 in the mechanism of mitochondrial complex I.

Galemou Yoga E, Parey K, Djurabekova A, Haapanen O, Siegmund K, Zwicker K, Sharma V, Zickermann V, Angerer H. Galemou Yoga E, et al. Among authors: haapanen o. Nat Commun. 2020 Nov 26;11(1):6008. doi: 10.1038/s41467-020-19778-7. Nat Commun. 2020. PMID: 33243981 Free PMC article.

8

Coupling of quinone dynamics to proton pumping in respiratory complex I.

Haapanen O, Reidelbach M, Sharma V. Haapanen O, et al. Biochim Biophys Acta Bioenerg. 2020 Dec 1;1861(12):148287. doi: 10.1016/j.bbabio.2020.148287. Epub 2020 Aug 7. Biochim Biophys Acta Bioenerg. 2020. PMID: 32777307 Free article. Review.

9

Proton motive function of the terminal antiporter-like subunit in respiratory complex I.

Djurabekova A, Haapanen O, Sharma V. Djurabekova A, et al. Among authors: haapanen o. Biochim Biophys Acta Bioenerg. 2020 Jul 1;1861(7):148185. doi: 10.1016/j.bbabio.2020.148185. Epub 2020 Mar 19. Biochim Biophys Acta Bioenerg. 2020. PMID: 32171794 Free article.

10

Oversized ubiquinones as molecular probes for structural dynamics of the ubiquinone reaction site in mitochondrial respiratory complex I.

Uno S, Masuya T, Shinzawa-Itoh K, Lasham J, Haapanen O, Shiba T, Inaoka DK, Sharma V, Murai M, Miyoshi H. Uno S, et al. Among authors: haapanen o. J Biol Chem. 2020 Feb 21;295(8):2449-2463. doi: 10.1074/jbc.RA119.012347. Epub 2020 Jan 17. J Biol Chem. 2020. PMID: 31953326 Free PMC article.

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