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Page 1
Improved Titer and Gene Transfer by Lentiviral Vectors Using Novel, Small β-Globin Locus Control Region Elements.
Morgan RA, Unti MJ, Aleshe B, Brown D, Osborne KS, Koziol C, Ayoub PG, Smith OB, O'Brien R, Tam C, Miyahira E, Ruiz M, Quintos JP, Senadheera S, Hollis RP, Kohn DB. Morgan RA, et al. Among authors: ayoub pg. Mol Ther. 2020 Jan 8;28(1):328-340. doi: 10.1016/j.ymthe.2019.09.020. Epub 2019 Sep 28. Mol Ther. 2020. PMID: 31628051 Free PMC article.
Creating New β-Globin-Expressing Lentiviral Vectors by High-Resolution Mapping of Locus Control Region Enhancer Sequences.
Morgan RA, Ma F, Unti MJ, Brown D, Ayoub PG, Tam C, Lathrop L, Aleshe B, Kurita R, Nakamura Y, Senadheera S, Wong RL, Hollis RP, Pellegrini M, Kohn DB. Morgan RA, et al. Among authors: ayoub pg. Mol Ther Methods Clin Dev. 2020 Apr 18;17:999-1013. doi: 10.1016/j.omtm.2020.04.006. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2020. PMID: 32426415 Free PMC article.
β-Thalassemia: all about that base, no cutting.
Ayoub PG, Kohn DB. Ayoub PG, et al. Blood. 2023 Mar 9;141(10):1098-1099. doi: 10.1182/blood.2022019350. Blood. 2023. PMID: 36893006 Free article. No abstract available.
Global and Local Manipulation of DNA Repair Mechanisms to Alter Site-Specific Gene Editing Outcomes in Hematopoietic Stem Cells.
Benitez EK, Lomova Kaufman A, Cervantes L, Clark DN, Ayoub PG, Senadheera S, Osborne K, Sanchez JM, Crisostomo RV, Wang X, Reuven N, Shaul Y, Hollis RP, Romero Z, Kohn DB. Benitez EK, et al. Among authors: ayoub pg. Front Genome Ed. 2020 Dec 10;2:601541. doi: 10.3389/fgeed.2020.601541. eCollection 2020. Front Genome Ed. 2020. PMID: 34713224 Free PMC article.
Outcomes following treatment for ADA-deficient severe combined immunodeficiency: a report from the PIDTC.
Cuvelier GDE, Logan BR, Prockop SE, Buckley RH, Kuo CY, Griffith LM, Liu X, Yip A, Hershfield MS, Ayoub PG, Moore TB, Dorsey MJ, O'Reilly RJ, Kapoor N, Pai SY, Kapadia M, Ebens CL, Forbes Satter LR, Burroughs LM, Petrovic A, Chellapandian D, Heimall J, Shyr DC, Rayes A, Bednarski JJ, Chandra S, Chandrakasan S, Gillio AP, Madden L, Quigg TC, Caywood EH, Dávila Saldaña BJ, DeSantes K, Eissa H, Goldman FD, Rozmus J, Shah AJ, Vander Lugt MT, Thakar MS, Parrott RE, Martinez C, Leiding JW, Torgerson TR, Pulsipher MA, Notarangelo LD, Cowan MJ, Dvorak CC, Haddad E, Puck JM, Kohn DB. Cuvelier GDE, et al. Among authors: ayoub pg. Blood. 2022 Aug 18;140(7):685-705. doi: 10.1182/blood.2022016196. Blood. 2022. PMID: 35671392 Free PMC article. Clinical Trial.
Lentiviral vectors for precise expression to treat X-linked lymphoproliferative disease.
Ayoub PG, Gensheimer J, Lathrop L, Juett C, Quintos J, Tam K, Reid J, Ma F, Tam C, McAuley GE, Brown D, Wu X, Zhang R, Bradford K, Hollis RP, Crooks GM, Kohn DB. Ayoub PG, et al. Mol Ther Methods Clin Dev. 2024 Aug 20;32(4):101323. doi: 10.1016/j.omtm.2024.101323. eCollection 2024 Dec 12. Mol Ther Methods Clin Dev. 2024. PMID: 39309261 Free PMC article.