Seok SM - Search Results

1

Membrane phospholipid remodeling modulates nonalcoholic steatohepatitis progression by regulating mitochondrial homeostasis.

Tian Y, Jellinek MJ, Mehta K, Seok SM, Kuo SH, Lu W, Shi R, Lee R, Lau GW, Kemper JK, Zhang K, Ford DA, Wang B. Tian Y, et al. Among authors: seok sm. Hepatology. 2024 Apr 1;79(4):882-897. doi: 10.1097/HEP.0000000000000375. Epub 2023 Apr 1. Hepatology. 2024. PMID: 36999536

2

Ligand-dependent regulation of the activity of the orphan nuclear receptor, small heterodimer partner (SHP), in the repression of bile acid biosynthetic CYP7A1 and CYP8B1 genes.

Miao J, Choi SE, Seok SM, Yang L, Zuercher WJ, Xu Y, Willson TM, Xu HE, Kemper JK. Miao J, et al. Among authors: seok sm. Mol Endocrinol. 2011 Jul;25(7):1159-69. doi: 10.1210/me.2011-0033. Epub 2011 May 12. Mol Endocrinol. 2011. PMID: 21566081 Free PMC article.

3

Genomic analysis of hepatic farnesoid X receptor binding sites reveals altered binding in obesity and direct gene repression by farnesoid X receptor in mice.

Lee J, Seok S, Yu P, Kim K, Smith Z, Rivas-Astroza M, Zhong S, Kemper JK. Lee J, et al. Hepatology. 2012 Jul;56(1):108-17. doi: 10.1002/hep.25609. Epub 2012 Apr 24. Hepatology. 2012. PMID: 22278336 Free PMC article.

4

Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor β-Klotho.

Fu T, Choi SE, Kim DH, Seok S, Suino-Powell KM, Xu HE, Kemper JK. Fu T, et al. Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16137-42. doi: 10.1073/pnas.1205951109. Epub 2012 Sep 17. Proc Natl Acad Sci U S A. 2012. PMID: 22988100 Free PMC article.

5

Bile acid signal-induced phosphorylation of small heterodimer partner by protein kinase Cζ is critical for epigenomic regulation of liver metabolic genes.

Seok S, Kanamaluru D, Xiao Z, Ryerson D, Choi SE, Suino-Powell K, Xu HE, Veenstra TD, Kemper JK. Seok S, et al. J Biol Chem. 2013 Aug 9;288(32):23252-63. doi: 10.1074/jbc.M113.452037. Epub 2013 Jul 3. J Biol Chem. 2013. PMID: 23824184 Free PMC article.

6

Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT.

Choi SE, Fu T, Seok S, Kim DH, Yu E, Lee KW, Kang Y, Li X, Kemper B, Kemper JK. Choi SE, et al. Aging Cell. 2013 Dec;12(6):1062-72. doi: 10.1111/acel.12135. Epub 2013 Aug 11. Aging Cell. 2013. PMID: 23834033 Free PMC article.

7

MicroRNA 34a inhibits beige and brown fat formation in obesity in part by suppressing adipocyte fibroblast growth factor 21 signaling and SIRT1 function.

Fu T, Seok S, Choi S, Huang Z, Suino-Powell K, Xu HE, Kemper B, Kemper JK. Fu T, et al. Mol Cell Biol. 2014 Nov 15;34(22):4130-42. doi: 10.1128/MCB.00596-14. Epub 2014 Sep 2. Mol Cell Biol. 2014. PMID: 25182532 Free PMC article.

8

Transcriptional regulation of autophagy by an FXR-CREB axis.

Seok S, Fu T, Choi SE, Li Y, Zhu R, Kumar S, Sun X, Yoon G, Kang Y, Zhong W, Ma J, Kemper B, Kemper JK. Seok S, et al. Nature. 2014 Dec 4;516(7529):108-11. doi: 10.1038/nature13949. Epub 2014 Nov 12. Nature. 2014. PMID: 25383523 Free PMC article.

9

Farnesoid X receptor-induced lysine-specific histone demethylase reduces hepatic bile acid levels and protects the liver against bile acid toxicity.

Kim YC, Fang S, Byun S, Seok S, Kemper B, Kemper JK. Kim YC, et al. Hepatology. 2015 Jul;62(1):220-31. doi: 10.1002/hep.27677. Epub 2015 Feb 27. Hepatology. 2015. PMID: 25545350 Free PMC article.

10

FXR Primes the Liver for Intestinal FGF15 Signaling by Transient Induction of β-Klotho.

Fu T, Kim YC, Byun S, Kim DH, Seok S, Suino-Powell K, Xu HE, Kemper B, Kemper JK. Fu T, et al. Mol Endocrinol. 2016 Jan;30(1):92-103. doi: 10.1210/me.2015-1226. Epub 2015 Oct 27. Mol Endocrinol. 2016. PMID: 26505219 Free PMC article.

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