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TSTEM-like CAR-T cells exhibit improved persistence and tumor control compared with conventional CAR-T cells in preclinical models.
Meyran D, Zhu JJ, Butler J, Tantalo D, MacDonald S, Nguyen TN, Wang M, Thio N, D'Souza C, Qin VM, Slaney C, Harrison A, Sek K, Petrone P, Thia K, Giuffrida L, Scott AM, Terry RL, Tran B, Desai J, Prince HM, Harrison SJ, Beavis PA, Kershaw MH, Solomon B, Ekert PG, Trapani JA, Darcy PK, Neeson PJ. Meyran D, et al. Among authors: zhu jj. Sci Transl Med. 2023 Apr 5;15(690):eabk1900. doi: 10.1126/scitranslmed.abk1900. Epub 2023 Apr 5. Sci Transl Med. 2023. PMID: 37018415
Chimeric Antigen Receptor beyond CAR-T Cells.
Qin VM, D'Souza C, Neeson PJ, Zhu JJ. Qin VM, et al. Among authors: zhu jj. Cancers (Basel). 2021 Jan 22;13(3):404. doi: 10.3390/cancers13030404. Cancers (Basel). 2021. PMID: 33499101 Free PMC article. Review.
CDK4/6 Inhibition Promotes Antitumor Immunity through the Induction of T-cell Memory.
Lelliott EJ, Kong IY, Zethoven M, Ramsbottom KM, Martelotto LG, Meyran D, Zhu JJ, Costacurta M, Kirby L, Sandow JJ, Lim L, Dominguez PM, Todorovski I, Haynes NM, Beavis PA, Neeson PJ, Hawkins ED, McArthur GA, Parish IA, Johnstone RW, Oliaro J, Sheppard KE, Kearney CJ, Vervoort SJ. Lelliott EJ, et al. Among authors: zhu jj. Cancer Discov. 2021 Oct;11(10):2582-2601. doi: 10.1158/2159-8290.CD-20-1554. Epub 2021 May 14. Cancer Discov. 2021. PMID: 33990344
Early-phenotype CAR-T cells for the treatment of pediatric cancers.
Meyran D, Terry RL, Zhu JJ, Haber M, Ziegler DS, Ekert PG, Trapani JA, Darcy PK, Neeson PJ. Meyran D, et al. Among authors: zhu jj. Ann Oncol. 2021 Nov;32(11):1366-1380. doi: 10.1016/j.annonc.2021.07.018. Epub 2021 Aug 8. Ann Oncol. 2021. PMID: 34375680 Free article. Review.
The efficacy of combination treatment with elotuzumab and lenalidomide is dependent on crosstalk between natural killer cells, monocytes and myeloma cells.
Richardson K, Keam SP, Zhu JJ, Meyran D, D'Souza C, Macdonald S, Campbell K, Robbins M, Bezman NA, Todd K, Quach H, Ritchie DS, Harrison SJ, Prince HM, Trapani JA, Jenkins MR, Beavis PA, Darcy PK, Neeson PJ. Richardson K, et al. Among authors: zhu jj. Haematologica. 2023 Jan 1;108(1):83-97. doi: 10.3324/haematol.2021.279930. Haematologica. 2023. PMID: 35770527 Free PMC article.
1,273 results