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Page 1
A novel orthotopic mouse model replicates human lung cancer cachexia.
van de Worp WRPH, Theys J, González AS, van der Heyden B, Verhaegen F, Hauser D, Caiment F, Smeets HJM, Schols AMWJ, van Helvoort A, Langen RCJ. van de Worp WRPH, et al. Among authors: caiment f. J Cachexia Sarcopenia Muscle. 2023 Jun;14(3):1410-1423. doi: 10.1002/jcsm.13222. Epub 2023 Apr 6. J Cachexia Sarcopenia Muscle. 2023. PMID: 37025071 Free PMC article.
A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity.
Kuepfer L, Clayton O, Thiel C, Cordes H, Nudischer R, Blank LM, Baier V, Heymans S, Caiment F, Roth A, Fluri DA, Kelm JM, Castell J, Selevsek N, Schlapbach R, Keun H, Hynes J, Sarkans U, Gmuender H, Herwig R, Niederer S, Schuchhardt J, Segall M, Kleinjans J. Kuepfer L, et al. Among authors: caiment f. Arch Toxicol. 2018 Jan;92(1):553-555. doi: 10.1007/s00204-017-2041-7. Epub 2017 Aug 29. Arch Toxicol. 2018. PMID: 28852801 Free PMC article. No abstract available.
The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance.
Wang C, Gong B, Bushel PR, Thierry-Mieg J, Thierry-Mieg D, Xu J, Fang H, Hong H, Shen J, Su Z, Meehan J, Li X, Yang L, Li H, Łabaj PP, Kreil DP, Megherbi D, Gaj S, Caiment F, van Delft J, Kleinjans J, Scherer A, Devanarayan V, Wang J, Yang Y, Qian HR, Lancashire LJ, Bessarabova M, Nikolsky Y, Furlanello C, Chierici M, Albanese D, Jurman G, Riccadonna S, Filosi M, Visintainer R, Zhang KK, Li J, Hsieh JH, Svoboda DL, Fuscoe JC, Deng Y, Shi L, Paules RS, Auerbach SS, Tong W. Wang C, et al. Among authors: caiment f. Nat Biotechnol. 2014 Sep;32(9):926-32. doi: 10.1038/nbt.3001. Epub 2014 Aug 24. Nat Biotechnol. 2014. PMID: 25150839 Free PMC article.
The Rat microRNA body atlas; Evaluation of the microRNA content of rat organs through deep sequencing and characterization of pancreas enriched miRNAs as biomarkers of pancreatic toxicity in the rat and dog.
Smith A, Calley J, Mathur S, Qian HR, Wu H, Farmen M, Caiment F, Bushel PR, Li J, Fisher C, Kirby P, Koenig E, Hall DG, Watson DE. Smith A, et al. Among authors: caiment f. BMC Genomics. 2016 Aug 30;17(1):694. doi: 10.1186/s12864-016-2956-z. BMC Genomics. 2016. PMID: 27576563 Free PMC article.
Towards the development of an omics data analysis framework.
Verheijen M, Tong W, Shi L, Gant TW, Seligman B, Caiment F. Verheijen M, et al. Among authors: caiment f. Regul Toxicol Pharmacol. 2020 Apr;112:104621. doi: 10.1016/j.yrtph.2020.104621. Epub 2020 Feb 19. Regul Toxicol Pharmacol. 2020. PMID: 32087354
Polymorphic microRNA-target interactions: a novel source of phenotypic variation.
Georges M, Clop A, Marcq F, Takeda H, Pirottin D, Hiard S, Tordoir X, Caiment F, Meish F, Bibé B, Bouix J, Elsen JM, Eychenne F, Laville E, Larzul C, Milenkovic D, Tobin J, Charlier AC. Georges M, et al. Among authors: caiment f. Cold Spring Harb Symp Quant Biol. 2006;71:343-50. doi: 10.1101/sqb.2006.71.056. Cold Spring Harb Symp Quant Biol. 2006. PMID: 17381315
Comparing in vitro human liver models to in vivo human liver using RNA-Seq.
Gupta R, Schrooders Y, Hauser D, van Herwijnen M, Albrecht W, Ter Braak B, Brecklinghaus T, Castell JV, Elenschneider L, Escher S, Guye P, Hengstler JG, Ghallab A, Hansen T, Leist M, Maclennan R, Moritz W, Tolosa L, Tricot T, Verfaillie C, Walker P, van de Water B, Kleinjans J, Caiment F. Gupta R, et al. Among authors: caiment f. Arch Toxicol. 2021 Feb;95(2):573-589. doi: 10.1007/s00204-020-02937-6. Epub 2020 Oct 27. Arch Toxicol. 2021. PMID: 33106934 Free PMC article.
Pharmacological inhibition of 17β-hydroxysteroid dehydrogenase impairs human endometrial cancer growth in an orthotopic xenograft mouse model.
Xanthoulea S, Konings GFJ, Saarinen N, Delvoux B, Kooreman LFS, Koskimies P, Häkkinen MR, Auriola S, D'Avanzo E, Walid Y, Verhaegen F, Lieuwes NG, Caiment F, Kruitwagen R; ENITEC; Romano A. Xanthoulea S, et al. Among authors: caiment f. Cancer Lett. 2021 Jun 28;508:18-29. doi: 10.1016/j.canlet.2021.03.019. Epub 2021 Mar 21. Cancer Lett. 2021. PMID: 33762202 Free article.
62 results