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Rational engineering of glycosaminoglycan-based Dickkopf-1 scavengers to improve bone regeneration.
Ruiz-Gómez G, Salbach-Hirsch J, Dürig JN, Köhler L, Balamurugan K, Rother S, Heidig SL, Moeller S, Schnabelrauch M, Furesi G, Pählig S, Guillem-Gloria PM, Hofbauer C, Hintze V, Pisabarro MT, Rademann J, Hofbauer LC. Ruiz-Gómez G, et al. Among authors: hofbauer c, hofbauer lc. Biomaterials. 2023 Jun;297:122105. doi: 10.1016/j.biomaterials.2023.122105. Epub 2023 Mar 31. Biomaterials. 2023. PMID: 37031548
Dickkopf1 fuels inflammatory cytokine responses.
Jaschke NP, Pählig S, Sinha A, Adolph TE, Colunga ML, Hofmann M, Wang A, Thiele S, Schwärzler J, Kleymann A, Gentzel M, Tilg H, Wielockx B, Hofbauer LC, Rauner M, Göbel A, Rachner TD. Jaschke NP, et al. Among authors: hofbauer lc. Commun Biol. 2022 Dec 20;5(1):1391. doi: 10.1038/s42003-022-04368-8. Commun Biol. 2022. PMID: 36539532 Free PMC article.
Small-molecule CBP/p300 histone acetyltransferase inhibition mobilizes leukocytes from the bone marrow via the endocrine stress response.
Jaschke NP, Breining D, Hofmann M, Pählig S, Baschant U, Oertel R, Traikov S, Grinenko T, Saettini F, Biondi A, Stylianou M, Bringmann H, Zhang C, Yoshida TM, Weidner H, Poller WC, Swirski FK, Göbel A, Hofbauer LC, Rauner M, Scheiermann C, Wang A, Rachner TD. Jaschke NP, et al. Among authors: hofbauer lc. Immunity. 2024 Feb 13;57(2):364-378.e9. doi: 10.1016/j.immuni.2024.01.005. Epub 2024 Jan 31. Immunity. 2024. PMID: 38301651 Free article.
439 results