Tan TZ - Search Results

1

Super-enhancer-driven TOX2 mediates oncogenesis in Natural Killer/T Cell Lymphoma.

Zhou J, Toh SH, Tan TK, Balan K, Lim JQ, Tan TZ, Xiong S, Jia Y, Ng SB, Peng Y, Jeyasekharan AD, Fan S, Lim ST, Ong CJ, Ong CK, Sanda T, Chng WJ. Zhou J, et al. Among authors: tan tk, tan tz. Mol Cancer. 2023 Apr 10;22(1):69. doi: 10.1186/s12943-023-01767-1. Mol Cancer. 2023. PMID: 37032358 Free PMC article.

2

Phosphatase of regenerating liver-3 is regulated by signal transducer and activator of transcription 3 in acute myeloid leukemia.

Zhou J, Chong PS, Lu X, Cheong LL, Bi C, Liu SC, Zhou Y, Tan TZ, Yang H, Chung TH, Zeng Q, Chng WJ. Zhou J, et al. Among authors: tan tz. Exp Hematol. 2014 Dec;42(12):1041-52.e1-2. doi: 10.1016/j.exphem.2014.08.001. Epub 2014 Aug 17. Exp Hematol. 2014. PMID: 25139404 Free article.

3

LIN28B Activation by PRL-3 Promotes Leukemogenesis and a Stem Cell-like Transcriptional Program in AML.

Zhou J, Chan ZL, Bi C, Lu X, Chong PS, Chooi JY, Cheong LL, Liu SC, Ching YQ, Zhou Y, Osato M, Tan TZ, Ng CH, Ng SB, Wang S, Zeng Q, Chng WJ. Zhou J, et al. Among authors: tan tz. Mol Cancer Res. 2017 Mar;15(3):294-303. doi: 10.1158/1541-7786.MCR-16-0275-T. Epub 2016 Dec 23. Mol Cancer Res. 2017. PMID: 28011885

4

Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia.

Zhou J, Bi C, Ching YQ, Chooi JY, Lu X, Quah JY, Toh SH, Chan ZL, Tan TZ, Chong PS, Chng WJ. Zhou J, et al. Among authors: tan tz. J Hematol Oncol. 2017 Jul 11;10(1):138. doi: 10.1186/s13045-017-0507-y. J Hematol Oncol. 2017. PMID: 28693523 Free PMC article.

5

X-linked inhibitor of apoptosis inhibition sensitizes acute myeloid leukemia cell response to TRAIL and chemotherapy through potentiated induction of proapoptotic machinery.

Zhou J, Lu X, Tan TZ, Chng WJ. Zhou J, et al. Among authors: tan tz. Mol Oncol. 2018 Jan;12(1):33-47. doi: 10.1002/1878-0261.12146. Epub 2017 Dec 1. Mol Oncol. 2018. PMID: 29063676 Free PMC article.

6

A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphatase.

Zhou J, Toh SH, Chan ZL, Quah JY, Chooi JY, Tan TZ, Chong PSY, Zeng Q, Chng WJ. Zhou J, et al. Among authors: tan tz. J Hematol Oncol. 2018 Mar 7;11(1):36. doi: 10.1186/s13045-018-0581-9. J Hematol Oncol. 2018. PMID: 29514683 Free PMC article.

7

NF-κB promotes the stem-like properties of leukemia cells by activation of LIN28B.

Zhou J, Chooi JY, Ching YQ, Quah JY, Toh SH, Ng Y, Tan TZ, Chng WJ. Zhou J, et al. Among authors: tan tz. World J Stem Cells. 2018 Apr 26;10(4):34-42. doi: 10.4252/wjsc.v10.i4.34. World J Stem Cells. 2018. PMID: 29707103 Free PMC article.

8

BET Bromodomain inhibition promotes De-repression of TXNIP and activation of ASK1-MAPK pathway in acute myeloid leukemia.

Zhou Y, Zhou J, Lu X, Tan TZ, Chng WJ. Zhou Y, et al. Among authors: tan tz. BMC Cancer. 2018 Jul 11;18(1):731. doi: 10.1186/s12885-018-4661-6. BMC Cancer. 2018. PMID: 29996811 Free PMC article.

9

Non-canonical activation of β-catenin by PRL-3 phosphatase in acute myeloid leukemia.

Chong PSY, Zhou J, Chooi JY, Chan ZL, Toh SHM, Tan TZ, Wee S, Gunaratne J, Zeng Q, Chng WJ. Chong PSY, et al. Among authors: tan tz. Oncogene. 2019 Feb;38(9):1508-1519. doi: 10.1038/s41388-018-0526-3. Epub 2018 Oct 10. Oncogene. 2019. PMID: 30305722

10

OTUD4 enhances TGFβ signalling through regulation of the TGFβ receptor complex.

Jaynes PW, Iyengar PV, Lui SKL, Tan TZ, Vasilevski N, Wright SCE, Verdile G, Jeyasekharan AD, Eichhorn PJA. Jaynes PW, et al. Among authors: tan tz. Sci Rep. 2020 Sep 24;10(1):15725. doi: 10.1038/s41598-020-72791-0. Sci Rep. 2020. PMID: 32973272 Free PMC article.

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