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suPAR links a dysregulated immune response to tissue inflammation and sepsis-induced acute kidney injury.
Nusshag C, Wei C, Hahm E, Hayek SS, Li J, Samelko B, Rupp C, Szudarek R, Speer C, Kälble F, Schaier M, Uhle F, Schmitt FC, Fiedler MO, Krautkrämer E, Cao Y, Rodriguez R, Merle U, Eugen-Olsen J, Zeier M, Weigand MA, Morath C, Brenner T, Reiser J. Nusshag C, et al. Among authors: li j. JCI Insight. 2023 Apr 10;8(7):e165740. doi: 10.1172/jci.insight.165740. JCI Insight. 2023. PMID: 37036003 Free PMC article.
Modification of kidney barrier function by the urokinase receptor.
Wei C, Möller CC, Altintas MM, Li J, Schwarz K, Zacchigna S, Xie L, Henger A, Schmid H, Rastaldi MP, Cowan P, Kretzler M, Parrilla R, Bendayan M, Gupta V, Nikolic B, Kalluri R, Carmeliet P, Mundel P, Reiser J. Wei C, et al. Among authors: li j. Nat Med. 2008 Jan;14(1):55-63. doi: 10.1038/nm1696. Epub 2007 Dec 16. Nat Med. 2008. PMID: 18084301
Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis.
Wei C, El Hindi S, Li J, Fornoni A, Goes N, Sageshima J, Maiguel D, Karumanchi SA, Yap HK, Saleem M, Zhang Q, Nikolic B, Chaudhuri A, Daftarian P, Salido E, Torres A, Salifu M, Sarwal MM, Schaefer F, Morath C, Schwenger V, Zeier M, Gupta V, Roth D, Rastaldi MP, Burke G, Ruiz P, Reiser J. Wei C, et al. Among authors: li j. Nat Med. 2011 Jul 31;17(8):952-60. doi: 10.1038/nm.2411. Nat Med. 2011. PMID: 21804539 Free PMC article.
Circulating suPAR in two cohorts of primary FSGS.
Wei C, Trachtman H, Li J, Dong C, Friedman AL, Gassman JJ, McMahan JL, Radeva M, Heil KM, Trautmann A, Anarat A, Emre S, Ghiggeri GM, Ozaltin F, Haffner D, Gipson DS, Kaskel F, Fischer DC, Schaefer F, Reiser J; PodoNet and FSGS CT Study Consortia. Wei C, et al. Among authors: li j. J Am Soc Nephrol. 2012 Dec;23(12):2051-9. doi: 10.1681/ASN.2012030302. Epub 2012 Nov 8. J Am Soc Nephrol. 2012. PMID: 23138488 Free PMC article.
Reduction of proteinuria through podocyte alkalinization.
Altintas MM, Moriwaki K, Wei C, Möller CC, Flesche J, Li J, Yaddanapudi S, Faridi MH, Gödel M, Huber TB, Preston RA, Jiang JX, Kerjaschki D, Sever S, Reiser J. Altintas MM, et al. Among authors: li j. J Biol Chem. 2014 Jun 20;289(25):17454-67. doi: 10.1074/jbc.M114.568998. Epub 2014 May 9. J Biol Chem. 2014. PMID: 24817115 Free PMC article.
Sphingomyelinase-like phosphodiesterase 3b expression levels determine podocyte injury phenotypes in glomerular disease.
Yoo TH, Pedigo CE, Guzman J, Correa-Medina M, Wei C, Villarreal R, Mitrofanova A, Leclercq F, Faul C, Li J, Kretzler M, Nelson RG, Lehto M, Forsblom C, Groop PH, Reiser J, Burke GW, Fornoni A, Merscher S. Yoo TH, et al. Among authors: li j. J Am Soc Nephrol. 2015 Jan;26(1):133-47. doi: 10.1681/ASN.2013111213. Epub 2014 Jun 12. J Am Soc Nephrol. 2015. PMID: 24925721 Free PMC article.
Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease.
Hahm E, Wei C, Fernandez I, Li J, Tardi NJ, Tracy M, Wadhwani S, Cao Y, Peev V, Zloza A, Lusciks J, Hayek SS, O'Connor C, Bitzer M, Gupta V, Sever S, Sykes DB, Scadden DT, Reiser J. Hahm E, et al. Among authors: li j. Nat Med. 2017 Jan;23(1):100-106. doi: 10.1038/nm.4242. Epub 2016 Dec 12. Nat Med. 2017. PMID: 27941791 Free PMC article.
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