Lu B - Search Results

1

Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.

Geng J, Khaket TP, Pan J, Li W, Zhang Y, Ping Y, Cobos Sillero MI, Lu B. Geng J, et al. Among authors: lu b. Dev Cell. 2023 Apr 10;58(7):597-615.e10. doi: 10.1016/j.devcel.2023.03.002. Dev Cell. 2023. PMID: 37040696 Free PMC article.

2

Polo Kinase Phosphorylates Miro to Control ER-Mitochondria Contact Sites and Mitochondrial Ca(2+) Homeostasis in Neural Stem Cell Development.

Lee S, Lee KS, Huh S, Liu S, Lee DY, Hong SH, Yu K, Lu B. Lee S, et al. Among authors: lu b. Dev Cell. 2016 Apr 18;37(2):174-189. doi: 10.1016/j.devcel.2016.03.023. Dev Cell. 2016. PMID: 27093086 Free PMC article.

3

Altered ER-mitochondria contact impacts mitochondria calcium homeostasis and contributes to neurodegeneration in vivo in disease models.

Lee KS, Huh S, Lee S, Wu Z, Kim AK, Kang HY, Lu B. Lee KS, et al. Among authors: lu b. Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8844-E8853. doi: 10.1073/pnas.1721136115. Epub 2018 Sep 5. Proc Natl Acad Sci U S A. 2018. PMID: 30185553 Free PMC article.

4

Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD.

Li S, Wu Z, Li Y, Tantray I, De Stefani D, Mattarei A, Krishnan G, Gao FB, Vogel H, Lu B. Li S, et al. Among authors: lu b. Cell Rep. 2020 Aug 4;32(5):107989. doi: 10.1016/j.celrep.2020.107989. Cell Rep. 2020. PMID: 32755582 Free PMC article.

5

Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease.

Rimal S, Li Y, Vartak R, Geng J, Tantray I, Li S, Huh S, Vogel H, Glabe C, Grinberg LT, Spina S, Seeley WW, Guo S, Lu B. Rimal S, et al. Among authors: lu b. Acta Neuropathol Commun. 2021 Oct 18;9(1):169. doi: 10.1186/s40478-021-01268-6. Acta Neuropathol Commun. 2021. PMID: 34663454 Free PMC article.

6

Prevention of ribosome collision-induced neuromuscular degeneration by SARS CoV-2-encoded Nsp1.

Wang X, Rimal S, Tantray I, Geng J, Bhurtel S, Khaket TP, Li W, Han Z, Lu B. Wang X, et al. Among authors: lu b. Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2202322119. doi: 10.1073/pnas.2202322119. Epub 2022 Sep 28. Proc Natl Acad Sci U S A. 2022. PMID: 36170200 Free PMC article.

7

The mTORC2/AKT/VCP axis is associated with quality control of the stalled translation of poly(GR) dipeptide repeats in C9-ALS/FTD.

Li Y, Geng J, Rimal S, Wang H, Liu X, Lu B, Li S. Li Y, et al. Among authors: lu b. J Biol Chem. 2023 Mar;299(3):102995. doi: 10.1016/j.jbc.2023.102995. Epub 2023 Feb 9. J Biol Chem. 2023. PMID: 36764521 Free PMC article.

8

Reverse electron transfer is activated during aging and contributes to aging and age-related disease.

Rimal S, Tantray I, Li Y, Pal Khaket T, Li Y, Bhurtel S, Li W, Zeng C, Lu B. Rimal S, et al. Among authors: lu b. EMBO Rep. 2023 Apr 5;24(4):e55548. doi: 10.15252/embr.202255548. Epub 2023 Feb 16. EMBO Rep. 2023. PMID: 36794623 Free PMC article.

9

Stalled translation by mitochondrial stress upregulates a CNOT4-ZNF598 ribosomal quality control pathway important for tissue homeostasis.

Geng J, Li S, Li Y, Wu Z, Bhurtel S, Rimal S, Khan D, Ohja R, Brandman O, Lu B. Geng J, et al. Among authors: lu b. Nat Commun. 2024 Feb 22;15(1):1637. doi: 10.1038/s41467-024-45525-3. Nat Commun. 2024. PMID: 38388640 Free PMC article.

10

Ribosome stalling during c-myc translation presents actionable cancer cell vulnerability.

Khaket TP, Rimal S, Wang X, Bhurtel S, Wu YC, Lu B. Khaket TP, et al. Among authors: lu b. PNAS Nexus. 2024 Aug 13;3(8):pgae321. doi: 10.1093/pnasnexus/pgae321. eCollection 2024 Aug. PNAS Nexus. 2024. PMID: 39161732 Free PMC article.

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