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Regulation of the HIF-1alpha level is essential for hematopoietic stem cells.
Takubo K, Goda N, Yamada W, Iriuchishima H, Ikeda E, Kubota Y, Shima H, Johnson RS, Hirao A, Suematsu M, Suda T. Takubo K, et al. Among authors: goda n. Cell Stem Cell. 2010 Sep 3;7(3):391-402. doi: 10.1016/j.stem.2010.06.020. Cell Stem Cell. 2010. PMID: 20804974 Free article.
p38α Activates Purine Metabolism to Initiate Hematopoietic Stem/Progenitor Cell Cycling in Response to Stress.
Karigane D, Kobayashi H, Morikawa T, Ootomo Y, Sakai M, Nagamatsu G, Kubota Y, Goda N, Matsumoto M, Nishimura EK, Soga T, Otsu K, Suematsu M, Okamoto S, Suda T, Takubo K. Karigane D, et al. Among authors: goda n. Cell Stem Cell. 2016 Aug 4;19(2):192-204. doi: 10.1016/j.stem.2016.05.013. Epub 2016 Jun 23. Cell Stem Cell. 2016. PMID: 27345838 Free article.
SLC15A4 mediates M1-prone metabolic shifts in macrophages and guards immune cells from metabolic stress.
Kobayashi T, Nguyen-Tien D, Sorimachi Y, Sugiura Y, Suzuki T, Karyu H, Shimabukuro-Demoto S, Uemura T, Okamura T, Taguchi T, Ueki K, Kato N, Goda N, Dohmae N, Takubo K, Suematsu M, Toyama-Sorimachi N. Kobayashi T, et al. Among authors: goda n. Proc Natl Acad Sci U S A. 2021 Aug 17;118(33):e2100295118. doi: 10.1073/pnas.2100295118. Proc Natl Acad Sci U S A. 2021. PMID: 34385317 Free PMC article.
Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis.
Watanuki S, Kobayashi H, Sugiura Y, Yamamoto M, Karigane D, Shiroshita K, Sorimachi Y, Fujita S, Morikawa T, Koide S, Oshima M, Nishiyama A, Murakami K, Haraguchi M, Tamaki S, Yamamoto T, Yabushita T, Tanaka Y, Nagamatsu G, Honda H, Okamoto S, Goda N, Tamura T, Nakamura-Ishizu A, Suematsu M, Iwama A, Suda T, Takubo K. Watanuki S, et al. Among authors: goda n. Elife. 2024 Apr 4;12:RP87674. doi: 10.7554/eLife.87674. Elife. 2024. PMID: 38573813 Free PMC article.
Collaboration between a cis-interacting natural killer cell receptor and membrane sphingolipid is critical for the phagocyte function.
Karyu H, Niki T, Sorimachi Y, Hata S, Shimabukuro-Demoto S, Hirabayashi T, Mukai K, Kasahara K, Takubo K, Goda N, Honke K, Taguchi T, Sorimachi H, Toyama-Sorimachi N. Karyu H, et al. Among authors: goda n. Front Immunol. 2024 Apr 24;15:1401294. doi: 10.3389/fimmu.2024.1401294. eCollection 2024. Front Immunol. 2024. PMID: 38720899 Free PMC article.
SDHAF1 confers metabolic resilience to aging hematopoietic stem cells by promoting mitochondrial ATP production.
Watanuki S, Kobayashi H, Sugiura Y, Yamamoto M, Karigane D, Shiroshita K, Sorimachi Y, Morikawa T, Fujita S, Shide K, Haraguchi M, Tamaki S, Mikawa T, Kondoh H, Nakano H, Sumiyama K, Nagamatsu G, Goda N, Okamoto S, Nakamura-Ishizu A, Shimoda K, Suematsu M, Suda T, Takubo K. Watanuki S, et al. Among authors: goda n. Cell Stem Cell. 2024 Aug 1;31(8):1145-1161.e15. doi: 10.1016/j.stem.2024.04.023. Epub 2024 May 20. Cell Stem Cell. 2024. PMID: 38772377
187 results