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Page 1
Engineering kinetics of TLR7/8 agonist release from bottlebrush prodrugs enables tumor-focused immune stimulation.
Bhagchandani SH, Vohidov F, Milling LE, Tong EY, Brown CM, Ramseier ML, Liu B, Fessenden TB, Nguyen HV, Kiel GR, Won L, Langer RS, Spranger S, Shalek AK, Irvine DJ, Johnson JA. Bhagchandani SH, et al. Among authors: langer rs. Sci Adv. 2023 Apr 21;9(16):eadg2239. doi: 10.1126/sciadv.adg2239. Epub 2023 Apr 19. Sci Adv. 2023. PMID: 37075115 Free PMC article.
Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination.
Tam HH, Melo MB, Kang M, Pelet JM, Ruda VM, Foley MH, Hu JK, Kumari S, Crampton J, Baldeon AD, Sanders RW, Moore JP, Crotty S, Langer R, Anderson DG, Chakraborty AK, Irvine DJ. Tam HH, et al. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6639-E6648. doi: 10.1073/pnas.1606050113. Epub 2016 Oct 4. Proc Natl Acad Sci U S A. 2016. PMID: 27702895 Free PMC article.
Trends in Therapeutic Conjugates: Bench to Clinic.
Rudra A, Li J, Shakur R, Bhagchandani S, Langer R. Rudra A, et al. Bioconjug Chem. 2020 Mar 18;31(3):462-473. doi: 10.1021/acs.bioconjchem.9b00828. Epub 2020 Feb 11. Bioconjug Chem. 2020. PMID: 31990184 Review.
Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation.
Mead BE, Hattori K, Levy L, Imada S, Goto N, Vukovic M, Sze D, Kummerlowe C, Matute JD, Duan J, Langer R, Blumberg RS, Ordovas-Montanes J, Yilmaz ÖH, Karp JM, Shalek AK. Mead BE, et al. Among authors: langer r. Nat Biomed Eng. 2022 Apr;6(4):476-494. doi: 10.1038/s41551-022-00863-9. Epub 2022 Mar 21. Nat Biomed Eng. 2022. PMID: 35314801 Free PMC article.
Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer.
Alsaiari SK, Nadeef S, Daristotle JL, Rothwell W, Du B, Garcia J, Zhang L, Sarmadi M, Forster TA, Menon N, Lin SQ, Tostanoski LH, Hachmann N, Wang EY, Ventura JD, Barouch DH, Langer R, Jaklenec A. Alsaiari SK, et al. Sci Adv. 2024 Mar 8;10(10):eadj6380. doi: 10.1126/sciadv.adj6380. Epub 2024 Mar 6. Sci Adv. 2024. PMID: 38446889 Free PMC article.
Addition to "Trends in Therapeutic Conjugates: Bench to Clinic".
Rudra A, Li J, Shakur R, Bhagchandani S, Langer R. Rudra A, et al. Bioconjug Chem. 2020 Apr 15;31(4):1209. doi: 10.1021/acs.bioconjchem.0c00136. Epub 2020 Mar 23. Bioconjug Chem. 2020. PMID: 32202413 No abstract available.
987 results