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A positive feedback loop controls Toxoplasma chronic differentiation.
Licon MH, Giuliano CJ, Chan AW, Chakladar S, Eberhard JN, Shallberg LA, Chandrasekaran S, Waldman BS, Koshy AA, Hunter CA, Lourido S. Licon MH, et al. Nat Microbiol. 2023 May;8(5):889-904. doi: 10.1038/s41564-023-01358-2. Epub 2023 Apr 20. Nat Microbiol. 2023. PMID: 37081202 Free PMC article.
Translation initiation factor eIF1.2 promotes Toxoplasma stage conversion by regulating levels of key differentiation factors.
Wang F, Holmes MJ, Hong HJ, Thaprawat P, Kannan G, Huynh MH, Schultz TL, Licon MH, Lourido S, Dong W, Querido JB, Sullivan WJ, O'Leary SE, Carruthers VB. Wang F, et al. Among authors: licon mh. bioRxiv [Preprint]. 2024 May 15:2023.11.03.565545. doi: 10.1101/2023.11.03.565545. bioRxiv. 2024. Update in: Nat Commun. 2024 May 23;15(1):4385. doi: 10.1038/s41467-024-48685-4 PMID: 37961607 Free PMC article. Updated. Preprint.