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Zoledronic acid promotes TLR-4-mediated M1 macrophage polarization in bisphosphonate-related osteonecrosis of the jaw.
Zhu W, Xu R, Du J, Fu Y, Li S, Zhang P, Liu L, Jiang H. Zhu W, et al. Among authors: fu y. FASEB J. 2019 Apr;33(4):5208-5219. doi: 10.1096/fj.201801791RR. Epub 2019 Jan 9. FASEB J. 2019. PMID: 30624969
Taken together, our findings suggest that TLR-4-mediated macrophage polarization participates in the pathogenesis of BRONJ in mice, and TLR-4 may be a potential target for the prevention and therapeutic treatment of BRONJ.-Zhu, W., Xu, R., Du, J., Fu, Y., Li, S., Zh …
Taken together, our findings suggest that TLR-4-mediated macrophage polarization participates in the pathogenesis of BRONJ in mice, and TLR- …
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