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The rate of platelet activation determines thrombus size and structure at arterial shear.
Mitchell JL, Dunster JL, Kriek N, Unsworth AJ, Sage T, Mohammed YMM, De Simone I, Taylor KA, Bye AP, Ólafsson G, Brunton M, Mark S, Dymott LD, Whyte A, Ruparelia N, Mckenna C, Gibbins JM, Jones CI. Mitchell JL, et al. Among authors: kriek n. J Thromb Haemost. 2023 Aug;21(8):2248-2259. doi: 10.1016/j.jtha.2023.03.044. Epub 2023 Apr 19. J Thromb Haemost. 2023. PMID: 37085037 Free article.
Antithrombotic actions of statins involve PECAM-1 signaling.
Moraes LA, Vaiyapuri S, Sasikumar P, Ali MS, Kriek N, Sage T, Gibbins JM. Moraes LA, et al. Among authors: kriek n. Blood. 2013 Oct 31;122(18):3188-96. doi: 10.1182/blood-2013-04-491845. Epub 2013 Sep 12. Blood. 2013. PMID: 24030383 Free PMC article.
Farnesoid X Receptor and Its Ligands Inhibit the Function of Platelets.
Moraes LA, Unsworth AJ, Vaiyapuri S, Ali MS, Sasikumar P, Sage T, Flora GD, Bye AP, Kriek N, Dorchies E, Molendi-Coste O, Dombrowicz D, Staels B, Bishop-Bailey D, Gibbins JM. Moraes LA, et al. Among authors: kriek n. Arterioscler Thromb Vasc Biol. 2016 Dec;36(12):2324-2333. doi: 10.1161/ATVBAHA.116.308093. Epub 2016 Oct 6. Arterioscler Thromb Vasc Biol. 2016. PMID: 27758768 Free PMC article.
RXR Ligands Negatively Regulate Thrombosis and Hemostasis.
Unsworth AJ, Flora GD, Sasikumar P, Bye AP, Sage T, Kriek N, Crescente M, Gibbins JM. Unsworth AJ, et al. Among authors: kriek n. Arterioscler Thromb Vasc Biol. 2017 May;37(5):812-822. doi: 10.1161/ATVBAHA.117.309207. Epub 2017 Mar 2. Arterioscler Thromb Vasc Biol. 2017. PMID: 28254816 Free PMC article.
Farnesoid X Receptor and Liver X Receptor Ligands Initiate Formation of Coated Platelets.
Unsworth AJ, Bye AP, Tannetta DS, Desborough MJR, Kriek N, Sage T, Allan HE, Crescente M, Yaqoob P, Warner TD, Jones CI, Gibbins JM. Unsworth AJ, et al. Among authors: kriek n. Arterioscler Thromb Vasc Biol. 2017 Aug;37(8):1482-1493. doi: 10.1161/ATVBAHA.117.309135. Epub 2017 Jun 15. Arterioscler Thromb Vasc Biol. 2017. PMID: 28619996 Free PMC article.
86 results