Gradel AKJ - Search Results

1

The dietary regulation of LEAP2 depends on meal composition in mice.

Gradel AKJ, Holm SK, Byberg S, Merkestein M, Hogendorf WFJ, Lund ML, Buijink JA, Damgaard J, Lykkesfeldt J, Holst B. Gradel AKJ, et al. FASEB J. 2023 Jun;37(6):e22923. doi: 10.1096/fj.202201828R. FASEB J. 2023. PMID: 37104087

2

Food intake rather than blood glucose levels affects the pharmacokinetic profile of insulin aspart in pigs.

Gradel AKJ, Kildegaard J, Porsgaard T, Lykkesfeldt J, Refsgaard HHF. Gradel AKJ, et al. Basic Clin Pharmacol Toxicol. 2021 Jun;128(6):783-794. doi: 10.1111/bcpt.13574. Epub 2021 Mar 8. Basic Clin Pharmacol Toxicol. 2021. PMID: 33626236 Free article.

3

Subcutaneous Administration of Insulin is Associated With Regional Differences in Injection Depot Variability and Kinetics in The Rat.

Gradel AKJ, Porsgaard T, Lykkesfeldt J, Brockhoff PB, Seested T, Refsgaard HHF. Gradel AKJ, et al. Exp Clin Endocrinol Diabetes. 2020 May;128(5):332-338. doi: 10.1055/a-0658-1089. Epub 2018 Aug 3. Exp Clin Endocrinol Diabetes. 2020. PMID: 30075480

4

Optimization of pig models for translation of subcutaneous pharmacokinetics of therapeutic proteins: Liraglutide, insulin aspart and insulin detemir.

Pedersen KM, Gradel AKJ, Ludvigsen TP, Christoffersen BØ, Fuglsang-Damgaard CA, Bendtsen KM, Madsen SH, Manfé V, Refsgaard HHF. Pedersen KM, et al. Among authors: gradel akj. Transl Res. 2022 Jan;239:71-84. doi: 10.1016/j.trsl.2021.08.005. Epub 2021 Aug 21. Transl Res. 2022. PMID: 34428585 Free article.

5

The counterregulatory response to hypoglycaemia in the pig.

Gradel AKJ, Kildegaard J, Ludvigsen TP, Porsgaard T, Schou-Pedersen AMV, Fels JJ, Lykkesfeldt J, Refsgaard HHF. Gradel AKJ, et al. Basic Clin Pharmacol Toxicol. 2020 Oct;127(4):278-286. doi: 10.1111/bcpt.13422. Epub 2020 May 11. Basic Clin Pharmacol Toxicol. 2020. PMID: 32343047 Free article.

6

Delayed insulin absorption correlates with alterations in subcutaneous depot kinetics in rats with diet-induced obesity.

Gradel AKJ, Porsgaard T, Brockhoff PB, Seested T, Lykkesfeldt J, Refsgaard HHF. Gradel AKJ, et al. Obes Sci Pract. 2019 Mar 18;5(3):281-288. doi: 10.1002/osp4.326. eCollection 2019 Jun. Obes Sci Pract. 2019. PMID: 31275602 Free PMC article.

7

Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability.

Gradel AKJ, Porsgaard T, Lykkesfeldt J, Seested T, Gram-Nielsen S, Kristensen NR, Refsgaard HHF. Gradel AKJ, et al. J Diabetes Res. 2018 Jul 4;2018:1205121. doi: 10.1155/2018/1205121. eCollection 2018. J Diabetes Res. 2018. PMID: 30116732 Free PMC article. Review.

8

Long-term diet-induced hypertension in rats is associated with reduced expression and function of small artery SK_Ca, IK_Ca, and Kir2.1 channels.

Gradel AKJ, Salomonsson M, Sørensen CM, Holstein-Rathlou NH, Jensen LJ. Gradel AKJ, et al. Clin Sci (Lond). 2018 Feb 28;132(4):461-474. doi: 10.1042/CS20171408. Print 2018 Feb 28. Clin Sci (Lond). 2018. PMID: 29436481

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