Rao A - Search Results

1

Neuronal APOE4 removal protects against tau-mediated gliosis, neurodegeneration and myelin deficits.

Koutsodendris N, Blumenfeld J, Agrawal A, Traglia M, Grone B, Zilberter M, Yip O, Rao A, Nelson MR, Hao Y, Thomas R, Yoon SY, Arriola P, Huang Y. Koutsodendris N, et al. Among authors: rao a. Nat Aging. 2023 Mar;3(3):275-296. doi: 10.1038/s43587-023-00368-3. Epub 2023 Feb 20. Nat Aging. 2023. PMID: 37118426 Free PMC article.

2

Too Much Tau in Interneurons Impairs Adult Hippocampal Neurogenesis in Alzheimer's Disease.

Najm R, Rao A, Huang Y. Najm R, et al. Among authors: rao a. Cell Stem Cell. 2020 Mar 5;26(3):297-299. doi: 10.1016/j.stem.2020.02.004. Cell Stem Cell. 2020. PMID: 32142656 Free article.

3

In Vivo Chimeric Alzheimer's Disease Modeling of Apolipoprotein E4 Toxicity in Human Neurons.

Najm R, Zalocusky KA, Zilberter M, Yoon SY, Hao Y, Koutsodendris N, Nelson M, Rao A, Taubes A, Jones EA, Huang Y. Najm R, et al. Among authors: rao a. Cell Rep. 2020 Jul 28;32(4):107962. doi: 10.1016/j.celrep.2020.107962. Cell Rep. 2020. PMID: 32726626 Free PMC article.

4

Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer's disease.

Zalocusky KA, Najm R, Taubes AL, Hao Y, Yoon SY, Koutsodendris N, Nelson MR, Rao A, Bennett DA, Bant J, Amornkul DJ, Xu Q, An A, Cisne-Thomson O, Huang Y. Zalocusky KA, et al. Among authors: rao a. Nat Neurosci. 2021 Jun;24(6):786-798. doi: 10.1038/s41593-021-00851-3. Epub 2021 May 6. Nat Neurosci. 2021. PMID: 33958804 Free PMC article.

5

Apolipoprotein E and Alzheimer's Disease: Findings, Hypotheses, and Potential Mechanisms.

Koutsodendris N, Nelson MR, Rao A, Huang Y. Koutsodendris N, et al. Among authors: rao a. Annu Rev Pathol. 2022 Jan 24;17:73-99. doi: 10.1146/annurev-pathmechdis-030421-112756. Epub 2021 Aug 30. Annu Rev Pathol. 2022. PMID: 34460318 Review.

6

Dentate gyrus and CA3 GABAergic interneurons bidirectionally modulate signatures of internal and external drive to CA1.

Aery Jones EA, Rao A, Zilberter M, Djukic B, Bant JS, Gillespie AK, Koutsodendris N, Nelson M, Yoon SY, Huang K, Yuan H, Gill TM, Huang Y, Frank LM. Aery Jones EA, et al. Among authors: rao a. Cell Rep. 2021 Dec 28;37(13):110159. doi: 10.1016/j.celrep.2021.110159. Cell Rep. 2021. PMID: 34965435 Free PMC article.

7

Neuronal APOE4-induced Early Hippocampal Network Hyperexcitability in Alzheimer's Disease Pathogenesis.

Tabuena DR, Jang SS, Grone B, Yip O, Aery Jones EA, Blumenfeld J, Liang Z, Koutsodendris N, Rao A, Ding L, Zhang AR, Hao Y, Xu Q, Yoon SY, Leon S, Huang Y, Zilberter M. Tabuena DR, et al. Among authors: rao a. bioRxiv [Preprint]. 2024 Jul 3:2023.08.28.555153. doi: 10.1101/2023.08.28.555153. bioRxiv. 2024. PMID: 37693533 Free PMC article. Preprint.

8

APOE4-promoted gliosis and degeneration in tauopathy are ameliorated by pharmacological inhibition of HMGB1 release.

Koutsodendris N, Blumenfeld J, Agrawal A, Traglia M, Yip O, Rao A, Kim MJ, Nelson MR, Wang YH, Grone B, Hao Y, Thomas R, Zilberter M, Yoon SY, Arriola P, Huang Y. Koutsodendris N, et al. Among authors: rao a. Cell Rep. 2023 Oct 31;42(10):113252. doi: 10.1016/j.celrep.2023.113252. Epub 2023 Oct 19. Cell Rep. 2023. PMID: 37863057 Free PMC article.

9

Lysosomal proteomics reveals mechanisms of neuronal apoE4associated lysosomal dysfunction.

Krogsaeter EK, McKetney J, Marquez A, Cakir Z, Stevenson E, Jang GM, Rao A, Zhou A, Huang Y, Krogan NJ, Swaney DL. Krogsaeter EK, et al. Among authors: rao a. bioRxiv [Preprint]. 2023 Oct 2:2023.10.02.560519. doi: 10.1101/2023.10.02.560519. bioRxiv. 2023. PMID: 37873080 Free PMC article. Preprint.

10

The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation.

Nelson MR, Liu P, Agrawal A, Yip O, Blumenfeld J, Traglia M, Kim MJ, Koutsodendris N, Rao A, Grone B, Hao Y, Yoon SY, Xu Q, De Leon S, Choenyi T, Thomas R, Lopera F, Quiroz YT, Arboleda-Velasquez JF, Reiman EM, Mahley RW, Huang Y. Nelson MR, et al. Among authors: rao a. Nat Neurosci. 2023 Dec;26(12):2104-2121. doi: 10.1038/s41593-023-01480-8. Epub 2023 Nov 13. Nat Neurosci. 2023. PMID: 37957317 Free PMC article.

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