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Spatial transcriptomic analysis of Sonic hedgehog medulloblastoma identifies that the loss of heterogeneity and promotion of differentiation underlies the response to CDK4/6 inhibition.
Vo T, Balderson B, Jones K, Ni G, Crawford J, Millar A, Tolson E, Singleton M, Kojic M, Robertson T, Walters S, Mulay O, Bhuva DD, Davis MJ, Wainwright BJ, Nguyen Q, Genovesi LA. Vo T, et al. Among authors: genovesi la. Genome Med. 2023 May 1;15(1):29. doi: 10.1186/s13073-023-01185-4. Genome Med. 2023. PMID: 37127652 Free PMC article.
Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma.
Genovesi LA, Millar A, Tolson E, Singleton M, Hassall E, Kojic M, Brighi C, Girard E, Andradas C, Kuchibhotla M, Bhuva DD, Endersby R, Gottardo NG, Bernard A, Adolphe C, Olson JM, Taylor MD, Davis MJ, Wainwright BJ. Genovesi LA, et al. Genome Med. 2021 Jun 21;13(1):103. doi: 10.1186/s13073-021-00920-z. Genome Med. 2021. PMID: 34154646 Free PMC article.
15 results