Webb TI - Search Results

1

BK channel modulation by positively charged peptides and auxiliary γ subunits mediated by the Ca2+-bowl site.

Chen G, Li Q, Webb TI, Hollywood MA, Yan J. Chen G, et al. Among authors: webb ti. J Gen Physiol. 2023 Jun 5;155(6):e202213237. doi: 10.1085/jgp.202213237. Epub 2023 May 2. J Gen Physiol. 2023. PMID: 37130264 Free PMC article.

2

Development of GoSlo-SR-5-69, a potent activator of large conductance Ca2+-activated K+ (BK) channels.

Roy S, Large RJ, Akande AM, Kshatri A, Webb TI, Domene C, Sergeant GP, McHale NG, Thornbury KD, Hollywood MA. Roy S, et al. Among authors: webb ti. Eur J Med Chem. 2014 Mar 21;75:426-37. doi: 10.1016/j.ejmech.2014.01.035. Epub 2014 Feb 3. Eur J Med Chem. 2014. PMID: 24561672

3

Effects of the novel BK (KCa 1.1) channel opener GoSlo-SR-5-130 are dependent on the presence of BKβ subunits.

Large RJ, Kshatri A, Webb TI, Roy S, Akande A, Bradley E, Sergeant GP, Thornbury KD, McHale NG, Hollywood MA. Large RJ, et al. Among authors: webb ti. Br J Pharmacol. 2015 May;172(10):2544-56. doi: 10.1111/bph.13085. Epub 2015 Mar 26. Br J Pharmacol. 2015. PMID: 25598230 Free PMC article.

4

Molecular mechanisms underlying the effect of the novel BK channel opener GoSlo: involvement of the S4/S5 linker and the S6 segment.

Webb TI, Kshatri AS, Large RJ, Akande AM, Roy S, Sergeant GP, McHale NG, Thornbury KD, Hollywood MA. Webb TI, et al. Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):2064-9. doi: 10.1073/pnas.1400555112. Epub 2015 Feb 4. Proc Natl Acad Sci U S A. 2015. PMID: 25653338 Free PMC article.

5

Structure-activity relationships of a novel group of large-conductance Ca(2+)-activated K(+) (BK) channel modulators: the GoSlo-SR family.

Roy S, Morayo Akande A, Large RJ, Webb TI, Camarasu C, Sergeant GP, McHale NG, Thornbury KD, Hollywood MA. Roy S, et al. Among authors: webb ti. ChemMedChem. 2012 Oct;7(10):1763-9. doi: 10.1002/cmdc.201200321. Epub 2012 Aug 28. ChemMedChem. 2012. PMID: 22930560

6

The cardiac sodium current Na(v)1.5 is functionally expressed in rabbit bronchial smooth muscle cells.

Bradley E, Webb TI, Hollywood MA, Sergeant GP, McHale NG, Thornbury KD. Bradley E, et al. Among authors: webb ti. Am J Physiol Cell Physiol. 2013 Aug 15;305(4):C427-35. doi: 10.1152/ajpcell.00034.2013. Epub 2013 Jun 19. Am J Physiol Cell Physiol. 2013. PMID: 23784541 Free article.

7

Investigation of L-type Ca(2+) current in the aganglionic bowel segment in Hirschsprung's disease.

Large RJ, Bradley E, Webb T, O'Donnell AM, Puri P, Hollywood MA, Thornbury KD, McHale NG, Sergeant GP. Large RJ, et al. Neurogastroenterol Motil. 2012 Dec;24(12):1126-e571. doi: 10.1111/nmo.12006. Epub 2012 Sep 4. Neurogastroenterol Motil. 2012. PMID: 22947173

8

Effects of new-generation TMEM16A inhibitors on calcium-activated chloride currents in rabbit urethral interstitial cells of Cajal.

Fedigan S, Bradley E, Webb T, Large RJ, Hollywood MA, Thornbury KD, McHale NG, Sergeant GP. Fedigan S, et al. Pflugers Arch. 2017 Nov;469(11):1443-1455. doi: 10.1007/s00424-017-2028-5. Epub 2017 Jul 21. Pflugers Arch. 2017. PMID: 28733893

9

Pharmacological characterization of TMEM16A currents.

Bradley E, Fedigan S, Webb T, Hollywood MA, Thornbury KD, McHale NG, Sergeant GP. Bradley E, et al. Channels (Austin). 2014;8(4):308-20. doi: 10.4161/chan.28065. Channels (Austin). 2014. PMID: 24642630 Free PMC article.

10

The cells and conductance mediating cholinergic neurotransmission in the murine proximal stomach.

Sung TS, Hwang SJ, Koh SD, Bayguinov Y, Peri LE, Blair PJ, Webb TI, Pardo DM, Rock JR, Sanders KM, Ward SM. Sung TS, et al. Among authors: webb ti. J Physiol. 2018 May 1;596(9):1549-1574. doi: 10.1113/JP275478. Epub 2018 Mar 23. J Physiol. 2018. PMID: 29430647 Free PMC article.

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