Stoddard B - Search Results

1

De novo design of energy transfer proteins housing excitonically coupled chlorophyll special pairs.

Ennist N, Wang S, Kennedy M, Curti M, Sutherland G, Vasilev C, Redler R, Maffeis V, Shareef S, Sica A, Hua A, Deshmukh A, Moyer A, Hicks D, Swartz A, Cacho R, Novy N, Bera A, Kang A, Sankaran B, Johnson M, Reppert M, Ekiert D, Bhabha G, Stewart L, Caram J, Stoddard B, Romero E, Hunter CN, Baker D. Ennist N, et al. Among authors: stoddard b. Res Sq [Preprint]. 2023 Apr 21:rs.3.rs-2736786. doi: 10.21203/rs.3.rs-2736786/v1. Res Sq. 2023. Update in: Nat Chem Biol. 2024 Jul;20(7):906-915. doi: 10.1038/s41589-024-01626-0 PMID: 37131790 Free PMC article. Updated. Preprint.

2

Design, activity, and structure of a highly specific artificial endonuclease.

Chevalier BS, Kortemme T, Chadsey MS, Baker D, Monnat RJ, Stoddard BL. Chevalier BS, et al. Mol Cell. 2002 Oct;10(4):895-905. doi: 10.1016/s1097-2765(02)00690-1. Mol Cell. 2002. PMID: 12419232 Free article.

3

Design of a novel globular protein fold with atomic-level accuracy.

Kuhlman B, Dantas G, Ireton GC, Varani G, Stoddard BL, Baker D. Kuhlman B, et al. Among authors: stoddard bl. Science. 2003 Nov 21;302(5649):1364-8. doi: 10.1126/science.1089427. Science. 2003. PMID: 14631033

4

Computational thermostabilization of an enzyme.

Korkegian A, Black ME, Baker D, Stoddard BL. Korkegian A, et al. Science. 2005 May 6;308(5723):857-60. doi: 10.1126/science.1107387. Science. 2005. PMID: 15879217 Free PMC article.

5

Computational design of a new hydrogen bond network and at least a 300-fold specificity switch at a protein-protein interface.

Joachimiak LA, Kortemme T, Stoddard BL, Baker D. Joachimiak LA, et al. J Mol Biol. 2006 Aug 4;361(1):195-208. doi: 10.1016/j.jmb.2006.05.022. Epub 2006 May 24. J Mol Biol. 2006. PMID: 16831445

6

Control of repeat-protein curvature by computational protein design.

Park K, Shen BW, Parmeggiani F, Huang PS, Stoddard BL, Baker D. Park K, et al. Nat Struct Mol Biol. 2015 Feb;22(2):167-74. doi: 10.1038/nsmb.2938. Epub 2015 Jan 12. Nat Struct Mol Biol. 2015. PMID: 25580576 Free PMC article.

7

Precise assembly of complex beta sheet topologies from de novo designed building blocks.

King IC, Gleixner J, Doyle L, Kuzin A, Hunt JF, Xiao R, Montelione GT, Stoddard BL, DiMaio F, Baker D. King IC, et al. Elife. 2015 Dec 9;4:e11012. doi: 10.7554/eLife.11012. Elife. 2015. PMID: 26650357 Free PMC article.

8

Rational design of α-helical tandem repeat proteins with closed architectures.

Doyle L, Hallinan J, Bolduc J, Parmeggiani F, Baker D, Stoddard BL, Bradley P. Doyle L, et al. Nature. 2015 Dec 24;528(7583):585-8. doi: 10.1038/nature16191. Epub 2015 Dec 16. Nature. 2015. PMID: 26675735 Free PMC article.

9

Sampling and energy evaluation challenges in ligand binding protein design.

Dou J, Doyle L, Jr Greisen P, Schena A, Park H, Johnsson K, Stoddard BL, Baker D. Dou J, et al. Protein Sci. 2017 Dec;26(12):2426-2437. doi: 10.1002/pro.3317. Epub 2017 Oct 30. Protein Sci. 2017. PMID: 28980354 Free PMC article.

10

De novo design of a fluorescence-activating β-barrel.

Dou J, Vorobieva AA, Sheffler W, Doyle LA, Park H, Bick MJ, Mao B, Foight GW, Lee MY, Gagnon LA, Carter L, Sankaran B, Ovchinnikov S, Marcos E, Huang PS, Vaughan JC, Stoddard BL, Baker D. Dou J, et al. Among authors: stoddard bl. Nature. 2018 Sep;561(7724):485-491. doi: 10.1038/s41586-018-0509-0. Epub 2018 Sep 12. Nature. 2018. PMID: 30209393 Free PMC article.

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