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An ACAT inhibitor suppresses SARS-CoV-2 replication and boosts antiviral T cell activity.
Wing PAC, Schmidt NM, Peters R, Erdmann M, Brown R, Wang H, Swadling L; COVIDsortium Investigators; Newman J, Thakur N, Shionoya K, Morgan SB, Hinks TS, Watashi K, Bailey D, Hansen SB, Davidson AD, Maini MK, McKeating JA. Wing PAC, et al. PLoS Pathog. 2023 May 3;19(5):e1011323. doi: 10.1371/journal.ppat.1011323. eCollection 2023 May. PLoS Pathog. 2023. PMID: 37134108 Free PMC article.
iCollections methodology: workflow, results and lessons learned.
Blagoderov V, Penn M, Sadka M, Hine A, Brooks S, Siebert DJ, Sleep C, Cafferty S, Cane E, Martin G, Toloni F, Wing P, Chainey J, Duffell L, Huxley R, Ledger S, McLaughlin C, Mazzetta G, Perera J, Crowther R, Douglas L, Durant J, Honey M, Huertas B, Howard T, Carter V, Albuquerque S, Paterson G, Kitching IJ. Blagoderov V, et al. Biodivers Data J. 2017 Sep 25;(5):e19893. doi: 10.3897/BDJ.5.e19893. eCollection 2017. Biodivers Data J. 2017. PMID: 29104435 Free PMC article.
A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis.
Wing PA, Davenne T, Wettengel J, Lai AG, Zhuang X, Chakraborty A, D'Arienzo V, Kramer C, Ko C, Harris JM, Schreiner S, Higgs M, Roessler S, Parish JL, Protzer U, Balfe P, Rehwinkel J, McKeating JA. Wing PA, et al. Life Sci Alliance. 2019 Mar 27;2(2):e201900355. doi: 10.26508/lsa.201900355. Print 2019 Apr. Life Sci Alliance. 2019. PMID: 30918010 Free PMC article.
A PCR assay to quantify patterns of HBV transcription.
D'Arienzo V, Magri A, Harris JM, Wing PAC, Ko C, Rubio CO, Revill PA, Protzer U, Balfe P, McKeating JA. D'Arienzo V, et al. Among authors: wing pac. J Gen Virol. 2021 Mar;102(3):001373. doi: 10.1099/jgv.0.001373. Epub 2019 Dec 17. J Gen Virol. 2021. PMID: 31846416 Free PMC article.
Cholesterol-modifying drugs in COVID-19.
Schmidt NM, Wing PAC, McKeating JA, Maini MK. Schmidt NM, et al. Among authors: wing pac. Oxf Open Immunol. 2020;1(1):iqaa001. doi: 10.1093/oxfimm/iqaa001. Epub 2020 Jun 18. Oxf Open Immunol. 2020. PMID: 33047740 Free PMC article.
Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter.
Wing PAC, Liu PJ, Harris JM, Magri A, Michler T, Zhuang X, Borrmann H, Minisini R, Frampton NR, Wettengel JM, Mailly L, D'Arienzo V, Riedl T, Nobre L, Weekes MP, Pirisi M, Heikenwalder M, Baumert TF, Hammond EM, Mole DR, Protzer U, Balfe P, McKeating JA. Wing PAC, et al. J Hepatol. 2021 Jul;75(1):64-73. doi: 10.1016/j.jhep.2020.12.034. Epub 2021 Jan 29. J Hepatol. 2021. PMID: 33516779 Free PMC article.
Circadian control of hepatitis B virus replication.
Zhuang X, Forde D, Tsukuda S, D'Arienzo V, Mailly L, Harris JM, Wing PAC, Borrmann H, Schilling M, Magri A, Rubio CO, Maidstone RJ, Iqbal M, Garzon M, Minisini R, Pirisi M, Butterworth S, Balfe P, Ray DW, Watashi K, Baumert TF, McKeating JA. Zhuang X, et al. Among authors: wing pac. Nat Commun. 2021 Mar 12;12(1):1658. doi: 10.1038/s41467-021-21821-0. Nat Commun. 2021. PMID: 33712578 Free PMC article.
The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells.
Zhuang X, Tsukuda S, Wrensch F, Wing PA, Schilling M, Harris JM, Borrmann H, Morgan SB, Cane JL, Mailly L, Thakur N, Conceicao C, Sanghani H, Heydmann L, Bach C, Ashton A, Walsh S, Tan TK, Schimanski L, Huang KA, Schuster C, Watashi K, Hinks TS, Jagannath A, Vausdevan SR, Bailey D, Baumert TF, McKeating JA. Zhuang X, et al. bioRxiv [Preprint]. 2021 Jun 28:2021.03.20.436163. doi: 10.1101/2021.03.20.436163. bioRxiv. 2021. Update in: iScience. 2021 Oct 22;24(10):103144. doi: 10.1016/j.isci.2021.103144 PMID: 33758862 Free PMC article. Updated. Preprint.
36 results