Begthel H - Search Results

1

Patient-derived head and neck cancer organoids allow treatment stratification and serve as a tool for biomarker validation and identification.

Millen R, De Kort WWB, Koomen M, van Son GJF, Gobits R, Penning de Vries B, Begthel H, Zandvliet M, Doornaert P, Raaijmakers CPJ, Geurts MH, Elias SG, van Es RJJ, de Bree R, Devriese LA, Willems SM, Kranenburg O, Driehuis E, Clevers H. Millen R, et al. Among authors: begthel h. Med. 2023 May 12;4(5):290-310.e12. doi: 10.1016/j.medj.2023.04.003. Med. 2023. PMID: 37178682 Free article.

2

Canonical Wnt signals are essential for homeostasis of the intestinal epithelium.

Pinto D, Gregorieff A, Begthel H, Clevers H. Pinto D, et al. Among authors: begthel h. Genes Dev. 2003 Jul 15;17(14):1709-13. doi: 10.1101/gad.267103. Genes Dev. 2003. PMID: 12865297 Free PMC article.

3

De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine.

Haramis AP, Begthel H, van den Born M, van Es J, Jonkheer S, Offerhaus GJ, Clevers H. Haramis AP, et al. Among authors: begthel h. Science. 2004 Mar 12;303(5664):1684-6. doi: 10.1126/science.1093587. Science. 2004. PMID: 15017003

4

EphB receptor activity suppresses colorectal cancer progression.

Batlle E, Bacani J, Begthel H, Jonkheer S, Gregorieff A, van de Born M, Malats N, Sancho E, Boon E, Pawson T, Gallinger S, Pals S, Clevers H. Batlle E, et al. Among authors: begthel h. Nature. 2005 Jun 23;435(7045):1126-30. doi: 10.1038/nature03626. Nature. 2005. PMID: 15973414

5

Expression pattern of Wnt signaling components in the adult intestine.

Gregorieff A, Pinto D, Begthel H, Destrée O, Kielman M, Clevers H. Gregorieff A, et al. Among authors: begthel h. Gastroenterology. 2005 Aug;129(2):626-38. doi: 10.1016/j.gastro.2005.06.007. Gastroenterology. 2005. PMID: 16083717

6

Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia.

Haramis AP, Hurlstone A, van der Velden Y, Begthel H, van den Born M, Offerhaus GJ, Clevers HC. Haramis AP, et al. Among authors: begthel h. EMBO Rep. 2006 Apr;7(4):444-9. doi: 10.1038/sj.embor.7400638. Epub 2006 Jan 27. EMBO Rep. 2006. PMID: 16439994 Free PMC article.

7

Prominin-1/CD133 marks stem cells and early progenitors in mouse small intestine.

Snippert HJ, van Es JH, van den Born M, Begthel H, Stange DE, Barker N, Clevers H. Snippert HJ, et al. Among authors: begthel h. Gastroenterology. 2009 Jun;136(7):2187-2194.e1. doi: 10.1053/j.gastro.2009.03.002. Epub 2009 Mar 24. Gastroenterology. 2009. PMID: 19324043

8

The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium.

Gregorieff A, Stange DE, Kujala P, Begthel H, van den Born M, Korving J, Peters PJ, Clevers H. Gregorieff A, et al. Among authors: begthel h. Gastroenterology. 2009 Oct;137(4):1333-45.e1-3. doi: 10.1053/j.gastro.2009.06.044. Epub 2009 Jun 21. Gastroenterology. 2009. PMID: 19549527

9

Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin.

Snippert HJ, Haegebarth A, Kasper M, Jaks V, van Es JH, Barker N, van de Wetering M, van den Born M, Begthel H, Vries RG, Stange DE, Toftgård R, Clevers H. Snippert HJ, et al. Among authors: begthel h. Science. 2010 Mar 12;327(5971):1385-9. doi: 10.1126/science.1184733. Science. 2010. PMID: 20223988

10

The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis.

Mahmoudi T, Boj SF, Hatzis P, Li VS, Taouatas N, Vries RG, Teunissen H, Begthel H, Korving J, Mohammed S, Heck AJ, Clevers H. Mahmoudi T, et al. Among authors: begthel h. PLoS Biol. 2010 Nov 16;8(11):e1000539. doi: 10.1371/journal.pbio.1000539. PLoS Biol. 2010. PMID: 21103407 Free PMC article.

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