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Page 1
Selective Wee1 Inhibitors Led to Antitumor Activity In Vitro and Correlated with Myelosuppression.
Guler S, DiPoto MC, Crespo A, Caldwell R, Doerfel B, Grossmann N, Ho K, Huck B, Jones CC, Lan R, Musil D, Potnick J, Schilke H, Sherer B, Simon S, Sirrenberg C, Zhang Z, Liu-Bujalski L. Guler S, et al. Among authors: musil d. ACS Med Chem Lett. 2023 Apr 7;14(5):566-576. doi: 10.1021/acsmedchemlett.2c00481. eCollection 2023 May 11. ACS Med Chem Lett. 2023. PMID: 37197456 Free PMC article.
Discovery of Cycloalkyl[c]thiophenes as Novel Scaffolds for Hypoxia-Inducible Factor-2α Inhibitors.
Buchstaller HP, Sala-Hojman A, Leiendecker M, Albers J, Anlauf U, Berges N, Dong L, Fuchß T, Germann M, Knehans T, Krier M, Lecomte M, Müller D, Müller SR, Leuthner B, Lindemann R, Musil D, Nowak M, Reither V, Rettig C, Schindler CEM, Pakulska U, Spuck D, Wegener A, Zarębski A. Buchstaller HP, et al. Among authors: musil d. J Med Chem. 2023 Jul 13;66(13):8666-8686. doi: 10.1021/acs.jmedchem.3c00332. Epub 2023 Jul 5. J Med Chem. 2023. PMID: 37403966
Discovery of quinazoline HPK1 inhibitors with high cellular potency.
Toure M, Johnson T, Li B, Schmidt R, Ma H, Neagu C, Lopez AU, Wang Y, Guler S, Xiao Y, Henkes R, Ho K, Zhang S, Chu CL, Gundra UM, Porichis F, Li L, Maurer CK, Fang Z, Musil D, DiPoto M, Friis E, Jones R, Jones C, Cummings J, Chekler E, Tanzer EM, Huck B, Sherer B. Toure M, et al. Among authors: musil d. Bioorg Med Chem. 2023 Sep 7;92:117423. doi: 10.1016/j.bmc.2023.117423. Epub 2023 Jul 27. Bioorg Med Chem. 2023. PMID: 37531921
Discovery of reversible and covalent TEAD 1 selective inhibitors MSC-1254 and MSC-5046 based on one scaffold.
Carswell E, Heinrich T, Petersson C, Gunera J, Garg S, Schwarz D, Schlesiger S, Fischer F, Eichhorn T, Calder M, Smith G, MacDonald E, Wilson H, Hazel K, Trivier E, Broome R, Balsiger A, Sirohi S, Musil D, Freire F, Schilke H, Dillon C, Wienke D. Carswell E, et al. Among authors: musil d. Bioorg Med Chem Lett. 2024 Dec 1;114:129981. doi: 10.1016/j.bmcl.2024.129981. Epub 2024 Oct 5. Bioorg Med Chem Lett. 2024. PMID: 39369801
What Are the Contraindications for Lateral or Medial Unicondylar Knee Arthroplasty?
Tarabichi S, Rui F, Deckey DG, Verhey JT, Van Schuyver P, Rashed M, Saleh U, Albelooshi A, He C, Jevsevar D, Musil D, Spangehl MJ, Bingham JS. Tarabichi S, et al. Among authors: musil d. J Arthroplasty. 2024 Oct 19:S0883-5403(24)01056-8. doi: 10.1016/j.arth.2024.10.043. Online ahead of print. J Arthroplasty. 2024. PMID: 39428006 Review. No abstract available.
On the humanization of VHHs: Prospective case studies, experimental and computational characterization of structural determinants for functionality.
Fernández-Quintero ML, Guarnera E, Musil D, Pekar L, Sellmann C, Freire F, Sousa RL, Santos SP, Freitas MC, Bandeiras TM, Silva MMS, Loeffler JR, Ward AB, Harwardt J, Zielonka S, Evers A. Fernández-Quintero ML, et al. Among authors: musil d. Protein Sci. 2024 Nov;33(11):e5176. doi: 10.1002/pro.5176. Protein Sci. 2024. PMID: 39422475 Free PMC article.
Tuning polymer-blood and polymer-cytoplasm membrane interactions by manipulating the architecture of poly(2-oxazoline) triblock copolymers.
Lobaz V, Liščáková V, Sedlák F, Musil D, Petrova SL, Šeděnková I, Pánek J, Kučka J, Konefał R, Tihlaříková E, Neděla V, Pankrác J, Šefc L, Hrubý M, Šácha P, Štěpánek P. Lobaz V, et al. Among authors: musil d. Colloids Surf B Biointerfaces. 2023 Nov;231:113564. doi: 10.1016/j.colsurfb.2023.113564. Epub 2023 Sep 21. Colloids Surf B Biointerfaces. 2023. PMID: 37742364 Free article.
118 results