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Page 1
Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation.
de Carvalho Ribeiro M, Iracheta-Vellve A, Babuta M, Calenda CD, Copeland C, Zhuang Y, Lowe PP, Hawryluk D, Catalano D, Cho Y, Barton B, Dasarathy S, McClain C, McCullough AJ, Mitchell MC, Nagy LE, Radaeva S, Lien E, Golenbock DT, Szabo G. de Carvalho Ribeiro M, et al. Among authors: nagy le. Hepatology. 2023 Jul 1;78(1):225-242. doi: 10.1097/HEP.0000000000000298. Epub 2023 Mar 3. Hepatology. 2023. PMID: 36862512
Randomized trial of anakinra plus zinc vs. prednisone for severe alcohol-associated hepatitis.
Gawrieh S, Dasarathy S, Tu W, Kamath PS, Chalasani NP, McClain CJ, Bataller R, Szabo G, Tang Q, Radaeva S, Barton B, Nagy LE, Shah VH, Sanyal AJ, Mitchell MC; AlcHepNet Investigators. Gawrieh S, et al. Among authors: nagy le. J Hepatol. 2024 May;80(5):684-693. doi: 10.1016/j.jhep.2024.01.031. Epub 2024 Feb 10. J Hepatol. 2024. PMID: 38342441 Clinical Trial.
Acute kidney injury in severe alcohol-associated hepatitis treated with anakinra plus zinc or prednisone.
Patidar KR, Tu W, Cotter TG, Simonetto DA, Asgharpour A, Jan MY, Tang Q, Yu Y, Li Y, Taiwo M, Thevkar Nagesh P, Dasarathy S, Kamath PS, McClain CJ, Chalasani N, Szabo G, Bataller R, Mitchell M, Mehal WZ, Nagy LE, Shah VH, Gawrieh S, Sanyal AJ; AlcHepNet Investigators. Patidar KR, et al. Among authors: nagy le. Hepatology. 2024 Jul 19. doi: 10.1097/HEP.0000000000001019. Online ahead of print. Hepatology. 2024. PMID: 39028887
A polygenic risk score for alcohol-associated cirrhosis among heavy drinkers with European ancestry.
Schwantes-An TH, Whitfield JB, Aithal GP, Atkinson SR, Bataller R, Botwin G, Chalasani NP, Cordell HJ, Daly AK, Darlay R, Day CP, Eyer F, Foroud T, Gawrieh S, Gleeson D, Goldman D, Haber PS, Jacquet JM, Lammert CS, Liang T, Liangpunsakul S, Masson S, Mathurin P, Moirand R, McQuillin A, Moreno C, Morgan MY, Mueller S, Müllhaupt B, Nagy LE, Nahon P, Nalpas B, Naveau S, Perney P, Pirmohamed M, Seitz HK, Soyka M, Stickel F, Thompson A, Thursz MR, Trépo E, Morgan TR, Seth D; GenomALC Consortium. Schwantes-An TH, et al. Among authors: nagy le. Hepatol Commun. 2024 May 10;8(6):e0431. doi: 10.1097/HC9.0000000000000431. eCollection 2024 Jun 1. Hepatol Commun. 2024. PMID: 38727677 Free PMC article.
Safety, Pharmacokinetics, and Efficacy Signals of Larsucosterol (DUR-928) in Alcohol-Associated Hepatitis.
Hassanein T, McClain CJ, Vatsalya V, Stein LL, Flamm SL, Martin P, Cave MC, Mitchell M Jr, Barton B, Nagy L, Szabo G, McCullough A, Dasarathy S, Shah J, Blevins C, Scott D, Krebs W, Brown JE, Lin W. Hassanein T, et al. Am J Gastroenterol. 2024 Jan 1;119(1):107-115. doi: 10.14309/ajg.0000000000002275. Epub 2023 Apr 3. Am J Gastroenterol. 2024. PMID: 37011138 Free PMC article.
Physiological processes underlying organ injury in alcohol abuse.
Souza-Smith FM, Lang CH, Nagy LE, Bailey SM, Parsons LH, Murray GJ. Souza-Smith FM, et al. Among authors: nagy le. Am J Physiol Endocrinol Metab. 2016 Sep 1;311(3):E605-19. doi: 10.1152/ajpendo.00270.2016. Epub 2016 Jul 19. Am J Physiol Endocrinol Metab. 2016. PMID: 27436613 Free PMC article. Review.
Role of Complement in Liver Diseases.
Prado LG, Nagy LE. Prado LG, et al. Among authors: nagy le. Semin Liver Dis. 2024 Nov 28. doi: 10.1055/s-0044-1795143. Online ahead of print. Semin Liver Dis. 2024. PMID: 39608405
Evidence that extracellular HSPB1 contributes to inflammation in alcohol-associated hepatitis.
Overstreet AC, Burge M, Bellar A, McMullen M, Czarnecki D, Huang E, Pathak V, Finney C, Vij R, Dasarathy S, Dasarathy J, Streem D, Welch N, Rotroff D, Schmitt AM, Nagy LE, Messer JS. Overstreet AC, et al. Among authors: nagy le. medRxiv [Preprint]. 2024 Sep 6:2024.09.06.24313193. doi: 10.1101/2024.09.06.24313193. medRxiv. 2024. PMID: 39281760 Free PMC article. Preprint.
218 results