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A master protocol to investigate a novel therapy acetyl-L-leucine for three ultra-rare neurodegenerative diseases: Niemann-Pick type C, the GM2 gangliosidoses, and ataxia telangiectasia.
Fields T, Patterson M, Bremova-Ertl T, Belcher G, Billington I, Churchill GC, Davis W, Evans W, Flint S, Galione A, Granzer U, Greenfield J, Karl R, Kay R, Lewi D, Mathieson T, Meyer T, Pangonis D, Platt FM, Tsang L, Verburg C, Factor M, Strupp M. Fields T, et al. Among authors: factor m. Trials. 2021 Jan 22;22(1):84. doi: 10.1186/s13063-020-05009-3. Trials. 2021. PMID: 33482890 Free PMC article.
Acetylation turns leucine into a drug by membrane transporter switching.
Churchill GC, Strupp M, Factor C, Bremova-Ertl T, Factor M, Patterson MC, Platt FM, Galione A. Churchill GC, et al. Among authors: factor m. Sci Rep. 2021 Aug 4;11(1):15812. doi: 10.1038/s41598-021-95255-5. Sci Rep. 2021. PMID: 34349180 Free PMC article.
Admitting Service and Outcome for Small Bowel Obstruction.
Thacker C, Lauer C, Nealon K, Walker C, Factor M. Thacker C, et al. Among authors: factor m. Am Surg. 2022 Apr;88(4):643-647. doi: 10.1177/00031348211054065. Epub 2021 Nov 18. Am Surg. 2022. PMID: 34791886
33 results