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Compound-42 alleviates acute kidney injury by targeting RIPK3-mediated necroptosis.
He XY, Wang F, Suo XG, Gu MZ, Wang JN, Xu CH, Dong YH, He Y, Zhang Y, Ji ML, Chen Y, Zhang MM, Fan YG, Wen JG, Jin J, Wang J, Li J, Zhuang CL, Liu MM, Meng XM. He XY, et al. Among authors: he y. Br J Pharmacol. 2023 Oct;180(20):2641-2660. doi: 10.1111/bph.16152. Epub 2023 Jul 1. Br J Pharmacol. 2023. PMID: 37248964 Free article.
Stratifin promotes renal dysfunction in ischemic and nephrotoxic AKI mouse models via enhancing RIPK3-mediated necroptosis.
Wang F, Wang JN, He XY, Suo XG, Li C, Ni WJ, Cai YT, He Y, Fang XY, Dong YH, Xing T, Yang YR, Zhang F, Zhong X, Zang HM, Liu MM, Li J, Meng XM, Jin J. Wang F, et al. Among authors: he xy, he y. Acta Pharmacol Sin. 2022 Feb;43(2):330-341. doi: 10.1038/s41401-021-00649-w. Epub 2021 Apr 8. Acta Pharmacol Sin. 2022. PMID: 33833407 Free PMC article.
Inhibition of METTL3 attenuates renal injury and inflammation by alleviating TAB3 m6A modifications via IGF2BP2-dependent mechanisms.
Wang JN, Wang F, Ke J, Li Z, Xu CH, Yang Q, Chen X, He XY, He Y, Suo XG, Li C, Yu JT, Jiang L, Ni WJ, Jin J, Liu MM, Shao W, Yang C, Gong Q, Chen HY, Li J, Wu YG, Meng XM. Wang JN, et al. Among authors: he xy, he y. Sci Transl Med. 2022 Apr 13;14(640):eabk2709. doi: 10.1126/scitranslmed.abk2709. Epub 2022 Apr 13. Sci Transl Med. 2022. PMID: 35417191
Targeting Necroptosis as a Promising Therapy for Alzheimer's Disease.
Zhao W, Liu Y, Xu L, He Y, Cai Z, Yu J, Zhang W, Xing C, Zhuang C, Qu Z. Zhao W, et al. Among authors: he y. ACS Chem Neurosci. 2022 Jun 15;13(12):1697-1713. doi: 10.1021/acschemneuro.2c00172. Epub 2022 May 23. ACS Chem Neurosci. 2022. PMID: 35607807 Review.
Cpd-0225 attenuates renal fibrosis via inhibiting ALK5.
Xie SS, Dong ZH, He Y, Chen ZW, Yang Q, Ma WX, Li C, Chen Y, Wang JN, Yu JT, Xu CH, Ni WJ, Hou R, Suo XG, Wen JG, Jin J, Li J, Liu MM, Meng XM. Xie SS, et al. Among authors: he y. Biochem Pharmacol. 2022 Oct;204:115240. doi: 10.1016/j.bcp.2022.115240. Epub 2022 Sep 5. Biochem Pharmacol. 2022. PMID: 36070847
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