Fang D - Search Results

1

The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes.

Wu SA, Shen C, Wei X, Zhang X, Wang S, Chen X, Torres M, Lu Y, Lin LL, Wang HH, Hunter AH, Fang D, Sun S, Ivanova MI, Lin Y, Qi L. Wu SA, et al. Among authors: fang d. Nat Commun. 2023 May 30;14(1):3132. doi: 10.1038/s41467-023-38690-4. Nat Commun. 2023. PMID: 37253728 Free PMC article.

2

IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation.

Sun S, Shi G, Sha H, Ji Y, Han X, Shu X, Ma H, Inoue T, Gao B, Kim H, Bu P, Guber RD, Shen X, Lee AH, Iwawaki T, Paton AW, Paton JC, Fang D, Tsai B, Yates JR 3rd, Wu H, Kersten S, Long Q, Duhamel GE, Simpson KW, Qi L. Sun S, et al. Among authors: fang d. Nat Cell Biol. 2015 Dec;17(12):1546-55. doi: 10.1038/ncb3266. Epub 2015 Nov 9. Nat Cell Biol. 2015. PMID: 26551274 Free PMC article.

3

The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity.

Xu Y, Zhao F, Qiu Q, Chen K, Wei J, Kong Q, Gao B, Melo-Cardenas J, Zhang B, Zhang J, Song J, Zhang DD, Zhang J, Fan Y, Li H, Fang D. Xu Y, et al. Among authors: fang d. Nat Commun. 2016 Jul 15;7:12073. doi: 10.1038/ncomms12073. Nat Commun. 2016. PMID: 27417417 Free PMC article.

4

The endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls a critical checkpoint in B cell development in mice.

Yang Y, Kong S, Zhang Y, Melo-Cardenas J, Gao B, Zhang Y, Zhang DD, Zhang B, Song J, Thorp E, Zhang K, Zhang J, Fang D. Yang Y, et al. Among authors: fang d. J Biol Chem. 2018 Aug 17;293(33):12934-12944. doi: 10.1074/jbc.RA117.001267. Epub 2018 Jun 15. J Biol Chem. 2018. PMID: 29907570 Free PMC article.

5

ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes.

Wei J, Yuan Y, Chen L, Xu Y, Zhang Y, Wang Y, Yang Y, Peek CB, Diebold L, Yang Y, Gao B, Jin C, Melo-Cardenas J, Chandel NS, Zhang DD, Pan H, Zhang K, Wang J, He F, Fang D. Wei J, et al. Among authors: fang d. Nat Commun. 2018 Sep 10;9(1):3659. doi: 10.1038/s41467-018-06091-7. Nat Commun. 2018. PMID: 30201971 Free PMC article.

6

Endoplasmic reticulum-associated degradation and beyond: The multitasking roles for HRD1 in immune regulation and autoimmunity.

Xu Y, Fang D. Xu Y, et al. Among authors: fang d. J Autoimmun. 2020 May;109:102423. doi: 10.1016/j.jaut.2020.102423. Epub 2020 Feb 11. J Autoimmun. 2020. PMID: 32057541 Free PMC article. Review.

7

Regulation of hepatic circadian metabolism by the E3 ubiquitin ligase HRD1-controlled CREBH/PPARα transcriptional program.

Kim H, Wei J, Song Z, Mottillo E, Samavati L, Zhang R, Li L, Chen X, Jena BP, Lin JD, Fang D, Zhang K. Kim H, et al. Among authors: fang d. Mol Metab. 2021 Jul;49:101192. doi: 10.1016/j.molmet.2021.101192. Epub 2021 Feb 13. Mol Metab. 2021. PMID: 33592335 Free PMC article.

8

Endoplasmic Reticulum Stress Signaling and the Pathogenesis of Hepatocarcinoma.

Wei J, Fang D. Wei J, et al. Among authors: fang d. Int J Mol Sci. 2021 Feb 11;22(4):1799. doi: 10.3390/ijms22041799. Int J Mol Sci. 2021. PMID: 33670323 Free PMC article. Review.

9

SEL1L-HRD1 ER-associated degradation suppresses hepatocyte hyperproliferation and liver cancer.

Bhattacharya A, Wei J, Song W, Gao B, Tian C, Wu SA, Wang J, Chen L, Fang D, Qi L. Bhattacharya A, et al. Among authors: fang d. iScience. 2022 Sep 24;25(10):105183. doi: 10.1016/j.isci.2022.105183. eCollection 2022 Oct 21. iScience. 2022. PMID: 36238898 Free PMC article.

10

Hepatic SEL1L-HRD1 ER-associated degradation regulates systemic iron homeostasis via ceruloplasmin.

Thepsuwan P, Bhattacharya A, Song Z, Hippleheuser S, Feng S, Wei X, Das NK, Sierra M, Wei J, Fang D, Huang YM, Zhang K, Shah YM, Sun S. Thepsuwan P, et al. Among authors: fang d. Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2212644120. doi: 10.1073/pnas.2212644120. Epub 2023 Jan 3. Proc Natl Acad Sci U S A. 2023. PMID: 36595688 Free PMC article.

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