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Co-cultures of colon cancer cells and cancer-associated fibroblasts recapitulate the aggressive features of mesenchymal-like colon cancer.
Strating E, Verhagen MP, Wensink E, Dünnebach E, Wijler L, Aranguren I, De la Cruz AS, Peters NA, Hageman JH, van der Net MMC, van Schelven S, Laoukili J, Fodde R, Roodhart J, Nierkens S, Snippert H, Gloerich M, Rinkes IB, Elias SG, Kranenburg O. Strating E, et al. Among authors: laoukili j. Front Immunol. 2023 May 16;14:1053920. doi: 10.3389/fimmu.2023.1053920. eCollection 2023. Front Immunol. 2023. PMID: 37261365 Free PMC article.
Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability.
Jongen JMJ, van der Waals LM, Trumpi K, Laoukili J, Peters NA, Schenning-van Schelven SJ, Govaert KM, Borel Rinkes IHM, Kranenburg O. Jongen JMJ, et al. Among authors: laoukili j. Oncotarget. 2017 Sep 21;8(49):86296-86311. doi: 10.18632/oncotarget.21145. eCollection 2017 Oct 17. Oncotarget. 2017. PMID: 29156796 Free PMC article.
30 results