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Page 1
MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer.
Zhu C, Soto-Feliciano YM, Morris JP, Huang CH, Koche RP, Ho YJ, Banito A, Chen CW, Shroff A, Tian S, Livshits G, Chen CC, Fennell M, Armstrong SA, Allis CD, Tschaharganeh DF, Lowe SW. Zhu C, et al. Among authors: tschaharganeh df. Elife. 2023 Jun 1;12:e80854. doi: 10.7554/eLife.80854. Elife. 2023. PMID: 37261974 Free PMC article.
Etiology-independent activation of the LTβ-LTβR-RELB axis drives aggressiveness and predicts poor prognosis in HCC.
Scherr AL, Nader L, Xu K, Elssner C, Ridder DA, Nichetti F, Mastel M, Fritzsche S, Kelmendi E, Schmitt N, Hoffmeister-Wittmann P, Weiler SME, Korell F, Albrecht T, Schwab M, Isele H, Kessler A, Hüllein J, Seretny A, Ye L, Urbanik T, Welte S, Leblond AL, Heilig CE, Rahbari M, Ali A, Gallage S, Lenoir B, Wilhelm N, Gärtner U, Ogrodnik SJ, Springfeld C, Tschaharganeh D, Fröhling S, Longerich T, Schulze-Bergkamen H, Jäger D, Brandl L, Schirmacher P, Straub BK, Weber A, De Toni EN, Goeppert B, Heikenwalder M, Jackstadt R, Roessler S, Breuhahn K, Köhler BC. Scherr AL, et al. Hepatology. 2024 Aug 1;80(2):278-294. doi: 10.1097/HEP.0000000000000657. Epub 2023 Nov 2. Hepatology. 2024. PMID: 37916976
Mitoferrin2 is a synthetic lethal target for chromosome 8p deleted cancers.
Krieg S, Rohde T, Rausch T, Butthof L, Wendler-Link L, Eckert C, Breuhahn K, Galy B, Korbel J, Billmann M, Breinig M, Tschaharganeh DF. Krieg S, et al. Among authors: tschaharganeh df. Genome Med. 2024 Jun 17;16(1):83. doi: 10.1186/s13073-024-01357-w. Genome Med. 2024. PMID: 38886830 Free PMC article.
Phosphatidylinositol 4-Kinase III Alpha Governs Cytoskeletal Organization for Invasiveness of Liver Cancer Cells.
Tran CS, Kersten J, Yan J, Breinig M, Huth T, Poth T, Colasanti O, Riedl T, Faure-Dupuy S, Diehl S, Verhoye L, Li TF, Lingemann M, Schult P, Ahlén G, Frelin L, Kühnel F, Vondran FWR, Breuhahn K, Meuleman P, Heikenwälder M, Schirmacher P, Bartenschlager R, Laketa V, Roessler S, Tschaharganeh DF, Sällberg M, Lohmann V. Tran CS, et al. Among authors: tschaharganeh df. Gastroenterology. 2024 Aug;167(3):522-537. doi: 10.1053/j.gastro.2024.04.009. Epub 2024 Apr 16. Gastroenterology. 2024. PMID: 38636680 Free article.
A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets.
Li X, Huang CH, Sánchez-Rivera FJ, Kennedy MC, Tschaharganeh DF, Morris JP 4th, Montinaro A, O'Rourke KP, Banito A, Wilkinson JE, Chen CC, Ho YJ, Dow LE, Tian S, Luan W, de Stanchina E, Zhang T, Gray NS, Walczak H, Lowe SW. Li X, et al. Among authors: tschaharganeh df. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2110557119. doi: 10.1073/pnas.2110557119. Epub 2022 Apr 20. Proc Natl Acad Sci U S A. 2022. PMID: 35442775 Free PMC article.
Histone H3K27 demethylase KDM6A is an epigenetic gatekeeper of mTORC1 signalling in cancer.
Revia S, Seretny A, Wendler L, Banito A, Eckert C, Breuer K, Mayakonda A, Lutsik P, Evert M, Ribback S, Gallage S, Chikh Bakri I, Breuhahn K, Schirmacher P, Heinrich S, Gaida MM, Heikenwälder M, Calvisi DF, Plass C, Lowe SW, Tschaharganeh DF. Revia S, et al. Among authors: tschaharganeh df. Gut. 2022 Aug;71(8):1613-1628. doi: 10.1136/gutjnl-2021-325405. Epub 2021 Sep 11. Gut. 2022. PMID: 34509979 Free PMC article.
Liver Inflammation and Hepatobiliary Cancers.
Leone V, Ali A, Weber A, Tschaharganeh DF, Heikenwalder M. Leone V, et al. Among authors: tschaharganeh df. Trends Cancer. 2021 Jul;7(7):606-623. doi: 10.1016/j.trecan.2021.01.012. Epub 2021 Mar 2. Trends Cancer. 2021. PMID: 33674229 Review.
Detection of Marker-Free Precision Genome Editing and Genetic Variation through the Capture of Genomic Signatures.
Billon P, Nambiar TS, Hayward SB, Zafra MP, Schatoff EM, Oshima K, Dunbar A, Breinig M, Park YC, Ryu HS, Tschaharganeh DF, Levine RL, Baer R, Ferrando A, Dow LE, Ciccia A. Billon P, et al. Among authors: tschaharganeh df. Cell Rep. 2020 Mar 10;30(10):3280-3295.e6. doi: 10.1016/j.celrep.2020.02.068. Cell Rep. 2020. PMID: 32160537 Free PMC article.
GPD1 Specifically Marks Dormant Glioma Stem Cells with a Distinct Metabolic Profile.
Rusu P, Shao C, Neuerburg A, Acikgöz AA, Wu Y, Zou P, Phapale P, Shankar TS, Döring K, Dettling S, Körkel-Qu H, Bekki G, Costa B, Guo T, Friesen O, Schlotter M, Heikenwalder M, Tschaharganeh DF, Bukau B, Kramer G, Angel P, Herold-Mende C, Radlwimmer B, Liu HK. Rusu P, et al. Among authors: tschaharganeh df. Cell Stem Cell. 2019 Aug 1;25(2):241-257.e8. doi: 10.1016/j.stem.2019.06.004. Epub 2019 Jul 11. Cell Stem Cell. 2019. PMID: 31303549 Free article.
44 results