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Page 1
The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity.
Ho P, Melms JC, Rogava M, Frangieh CJ, Poźniak J, Shah SB, Walsh Z, Kyrysyuk O, Amin AD, Caprio L, Fullerton BT, Soni RK, Ager CR, Biermann J, Wang Y, Khosravi-Maharlooei M, Zanetti G, Mu M, Fatima H, Moore EK, Vasan N, Bakhoum SF, Reiner SL, Bernatchez C, Sykes M, Mace EM, Wucherpfennig KW, Schadendorf D, Bechter O, Shah P, Schwartz GK, Marine JC, Izar B. Ho P, et al. Among authors: schadendorf d. Cancer Cell. 2023 Jul 10;41(7):1207-1221.e12. doi: 10.1016/j.ccell.2023.05.014. Epub 2023 Jun 15. Cancer Cell. 2023. PMID: 37327789 Free PMC article.
Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses.
Bayerl F, Meiser P, Donakonda S, Hirschberger A, Lacher SB, Pedde AM, Hermann CD, Elewaut A, Knolle M, Ramsauer L, Rudolph TJ, Grassmann S, Öllinger R, Kirchhammer N, Trefny M, Anton M, Wohlleber D, Höchst B, Zaremba A, Krüger A, Rad R, Obenauf AC, Schadendorf D, Zippelius A, Buchholz VR, Schraml BU, Böttcher JP. Bayerl F, et al. Among authors: schadendorf d. Immunity. 2023 Jun 13;56(6):1341-1358.e11. doi: 10.1016/j.immuni.2023.05.011. Immunity. 2023. PMID: 37315536 Free article.
Proteasome inhibition potentiates Kv1.3 potassium channel expression as therapeutic target in drug-sensitive and -resistant human melanoma cells.
Cammann C, Kulla J, Wiebusch L, Walz C, Zhao F, Lowinus T, Topfstedt E, Mishra N, Henklein P, Bommhardt U, Bossaller L, Hagemeier C, Schadendorf D, Schmidt B, Paschen A, Seifert U. Cammann C, et al. Among authors: schadendorf d. Biomed Pharmacother. 2023 Dec;168:115635. doi: 10.1016/j.biopha.2023.115635. Epub 2023 Oct 8. Biomed Pharmacother. 2023. PMID: 37816303 Free article.
Genomic heterogeneity and ploidy identify patients with intrinsic resistance to PD-1 blockade in metastatic melanoma.
Tarantino G, Ricker CA, Wang A, Ge W, Aprati TJ, Huang AY, Madha S, Chen J, Shi Y, Glettig M, Feng CH, Frederick DT, Freeman S, Holovatska MM, Manos MP, Zimmer L, Rösch A, Zaremba A, Livingstone E, Jameson JC, Saghafian S, Lee A, Zhao K, Morris LGT, Reardon B, Park J, Elmarakeby HA, Schilling B, Giobbie-Hurder A, Vokes NI, Buchbinder EI, Flaherty KT, Haq R, Wu CJ, Boland GM, Hodi FS, Van Allen EM, Schadendorf D, Liu D. Tarantino G, et al. Among authors: schadendorf d. Sci Adv. 2024 Nov 29;10(48):eadp4670. doi: 10.1126/sciadv.adp4670. Epub 2024 Nov 27. Sci Adv. 2024. PMID: 39602539
Cutaneous melanoma: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
Amaral T, Ottaviano M, Arance A, Blank C, Chiarion-Sileni V, Donia M, Dummer R, Garbe C, Gershenwald JE, Gogas H, Guckenberger M, Haanen J, Hamid O, Hauschild A, Höller C, Lebbé C, Lee RJ, Long GV, Lorigan P, Couselo EM, Nathan P, Robert C, Romano E, Schadendorf D, Sondak V, Suijkerbuijk KPM, van Akkooi ACJ, Michelin O, Ascierto PA; ESMO Guidelines Committee. Amaral T, et al. Among authors: schadendorf d. Ann Oncol. 2024 Nov 13:S0923-7534(24)04912-3. doi: 10.1016/j.annonc.2024.11.006. Online ahead of print. Ann Oncol. 2024. PMID: 39550033 No abstract available.
Adjuvant Use of Pembrolizumab for Stage III Melanoma in a Real-World Setting in Europe.
Weichenthal M, Mangana J, Gavrilova I, Lugowska I, Shalamanova GK, Kandolf L, Chiarion-Sileni V, Mohr P, Karanikolova TS, Teterycz P, Espinosa E, Schnecko P, Cheng P, Bender M, Jiang S, Burke T, Ascierto PA, Gogas H, Rodas IM, Rutkowski P, Schadendorf D, Dummer R, For The EUMelaReg Consortium. Weichenthal M, et al. Among authors: schadendorf d. Cancers (Basel). 2024 Oct 22;16(21):3558. doi: 10.3390/cancers16213558. Cancers (Basel). 2024. PMID: 39517999 Free PMC article.
Pooled Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone in Patients With Advanced Melanoma.
Long GV, Larkin J, Schadendorf D, Grob JJ, Lao CD, Márquez-Rodas I, Wagstaff J, Lebbé C, Pigozzo J, Robert C, Ascierto PA, Atkinson V, Postow MA, Atkins MB, Sznol M, Callahan MK, Topalian SL, Sosman JA, Kotapati S, Thakkar PK, Ritchings C, Pe Benito M, Re S, Soleymani S, Hodi FS. Long GV, et al. Among authors: schadendorf d. J Clin Oncol. 2024 Nov 6:JCO2400400. doi: 10.1200/JCO.24.00400. Online ahead of print. J Clin Oncol. 2024. PMID: 39504507
BioKGrapher: Initial evaluation of automated knowledge graph construction from biomedical literature.
Schäfer H, Idrissi-Yaghir A, Arzideh K, Damm H, Pakull TMG, Schmidt CS, Bahn M, Lodde G, Livingstone E, Schadendorf D, Nensa F, Horn PA, Friedrich CM. Schäfer H, et al. Among authors: schadendorf d. Comput Struct Biotechnol J. 2024 Oct 17;24:639-660. doi: 10.1016/j.csbj.2024.10.017. eCollection 2024 Dec. Comput Struct Biotechnol J. 2024. PMID: 39502384 Free PMC article.
Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis.
Shelton SD, House S, Martins Nascentes Melo L, Ramesh V, Chen Z, Wei T, Wang X, Llamas CB, Venigalla SSK, Menezes CJ, Allies G, Krystkiewicz J, Rösler J, Meckelmann SW, Zhao P, Rambow F, Schadendorf D, Zhao Z, Gill JG, DeBerardinis RJ, Morrison SJ, Tasdogan A, Mishra P. Shelton SD, et al. Among authors: schadendorf d. Sci Adv. 2024 Nov;10(44):eadk8801. doi: 10.1126/sciadv.adk8801. Epub 2024 Nov 1. Sci Adv. 2024. PMID: 39485847 Free PMC article.
1,107 results