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Page 1
Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells.
Vandekeere S, Dubois C, Kalucka J, Sullivan MR, García-Caballero M, Goveia J, Chen R, Diehl FF, Bar-Lev L, Souffreau J, Pircher A, Kumar S, Vinckier S, Hirabayashi Y, Furuya S, Schoonjans L, Eelen G, Ghesquière B, Keshet E, Li X, Vander Heiden MG, Dewerchin M, Carmeliet P. Vandekeere S, et al. Among authors: souffreau j. Cell Metab. 2018 Oct 2;28(4):573-587.e13. doi: 10.1016/j.cmet.2018.06.009. Epub 2018 Jul 12. Cell Metab. 2018. PMID: 30017355 Free article.
Role and therapeutic potential of dietary ketone bodies in lymph vessel growth.
García-Caballero M, Zecchin A, Souffreau J, Truong AK, Teuwen LA, Vermaelen W, Martín-Pérez R, de Zeeuw P, Bouché A, Vinckier S, Cornelissen I, Eelen G, Ghesquière B, Mazzone M, Dewerchin M, Carmeliet P. García-Caballero M, et al. Among authors: souffreau j. Nat Metab. 2019 Jul;1(7):666-675. doi: 10.1038/s42255-019-0087-y. Epub 2019 Jul 12. Nat Metab. 2019. PMID: 32694649
Role of glutamine synthetase in angiogenesis beyond glutamine synthesis.
Eelen G, Dubois C, Cantelmo AR, Goveia J, Brüning U, DeRan M, Jarugumilli G, van Rijssel J, Saladino G, Comitani F, Zecchin A, Rocha S, Chen R, Huang H, Vandekeere S, Kalucka J, Lange C, Morales-Rodriguez F, Cruys B, Treps L, Ramer L, Vinckier S, Brepoels K, Wyns S, Souffreau J, Schoonjans L, Lamers WH, Wu Y, Haustraete J, Hofkens J, Liekens S, Cubbon R, Ghesquière B, Dewerchin M, Gervasio FL, Li X, van Buul JD, Wu X, Carmeliet P. Eelen G, et al. Among authors: souffreau j. Nature. 2018 Sep;561(7721):63-69. doi: 10.1038/s41586-018-0466-7. Epub 2018 Aug 29. Nature. 2018. PMID: 30158707 Free article.
Notch3 Arg170Cys knock-in mice display pathologic and clinical features of the neurovascular disorder cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.
Wallays G, Nuyens D, Silasi-Mansat R, Souffreau J, Callaerts-Vegh Z, Van Nuffelen A, Moons L, D'Hooge R, Lupu F, Carmeliet P, Collen D, Dewerchin M. Wallays G, et al. Among authors: souffreau j. Arterioscler Thromb Vasc Biol. 2011 Dec;31(12):2881-8. doi: 10.1161/ATVBAHA.111.237859. Epub 2011 Sep 22. Arterioscler Thromb Vasc Biol. 2011. PMID: 21940951
The gluconeogenesis enzyme PCK2 has a non-enzymatic role in proteostasis in endothelial cells.
de Zeeuw P, Treps L, García-Caballero M, Harjes U, Kalucka J, De Legher C, Brepoels K, Peeters K, Vinckier S, Souffreau J, Bouché A, Taverna F, Dehairs J, Talebi A, Ghesquière B, Swinnen J, Schoonjans L, Eelen G, Dewerchin M, Carmeliet P. de Zeeuw P, et al. Among authors: souffreau j. Commun Biol. 2024 May 23;7(1):618. doi: 10.1038/s42003-024-06186-6. Commun Biol. 2024. PMID: 38783087 Free PMC article.