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IL-11 induces NLRP3 inflammasome activation in monocytes and inflammatory cell migration to the central nervous system.
Seyedsadr M, Wang Y, Elzoheiry M, Shree Gopal S, Jang S, Duran G, Chervoneva I, Kasimoglou E, Wrobel JA, Hwang D, Garifallou J, Zhang X, Khan TH, Lorenz U, Su M, Ting JP, Broux B, Rostami A, Miskin D, Markovic-Plese S. Seyedsadr M, et al. Among authors: wrobel ja. Proc Natl Acad Sci U S A. 2023 Jun 27;120(26):e2221007120. doi: 10.1073/pnas.2221007120. Epub 2023 Jun 20. Proc Natl Acad Sci U S A. 2023. PMID: 37339207 Free PMC article.
STING-induced regulatory B cells compromise NK function in cancer immunity.
Li S, Mirlekar B, Johnson BM, Brickey WJ, Wrobel JA, Yang N, Song D, Entwistle S, Tan X, Deng M, Cui Y, Li W, Vincent BG, Gale M Jr, Pylayeva-Gupta Y, Ting JP. Li S, et al. Among authors: wrobel ja. Nature. 2022 Oct;610(7931):373-380. doi: 10.1038/s41586-022-05254-3. Epub 2022 Oct 5. Nature. 2022. PMID: 36198789 Free PMC article.
Epigenomic, transcriptomic and proteomic characterizations of reference samples.
Nepal C, Chen W, Chen Z, Wrobel JA, Xie L, Liao W, Xiao C, Farmer A, Moos M Jr, Jones W, Chen X, Wang C. Nepal C, et al. Among authors: wrobel ja. bioRxiv [Preprint]. 2024 Sep 17:2024.09.09.612110. doi: 10.1101/2024.09.09.612110. bioRxiv. 2024. PMID: 39314461 Free PMC article. Preprint.
Novel brain-penetrant inhibitor of G9a methylase blocks Alzheimer's disease proteopathology for precision medication.
Xie L, Sheehy RN, Xiong Y, Muneer A, Wrobel JA, Park KS, Velez J, Liu J, Luo YJ, Li YD, Quintanilla L, Li Y, Xu C, Deshmukh M, Wen Z, Jin J, Song J, Chen X. Xie L, et al. Among authors: wrobel ja. medRxiv [Preprint]. 2023 Oct 26:2023.10.25.23297491. doi: 10.1101/2023.10.25.23297491. medRxiv. 2023. PMID: 37961307 Free PMC article. Preprint.
23 results